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Record W4394264530 · doi:10.6084/m9.figshare.15253977

Additional file 1 of Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

2021· dataset· en· W4394264530 on OpenAlexaff
Anna Morra, Maria Escala-Garcia, Jonathan Beesley, Renske Keeman, Sander Canisius, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton‐Culver, Volker Arndt, Paul L. Auer, Annelie Augustinsson, Laura E. Beane Freeman, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Stig E. Bojesen, Manjeet K. Bolla, Hermann Brenner, Thomas Brüning, Saundra S. Buys, Bette J. Caan, Daniele Campa, Federico Canzian, Jose E. Castelao, Jenny Chang‐Claude, Stephen J. Chanock, Ting‐Yuan David Cheng, Christine L. Clarke, Sarah V. Colonna, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Joe Dennis, Thilo Dörk, Laure Dossus, Alison M. Dunning, Miriam Dwek, Arif B. Ekici, A. Heather Eliassen, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Henrik Flyger, Lin Fritschi, Manuela Gago-Domínguez, José Á. García-Sáenz, Graham G. Giles, Mervi Grip, Pascal Guénel, Melanie Gündert, Eric Hahnen, Christopher A. Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Steven N. Hart, Jaana M. Hartikainen, Arndt Hartmann, Wei He, Maartje J. Hooning, Reiner Hoppe, John L. Hopper, Anthony Howell, David J. Hunter, Agnes Jager, Anna Jakubowska, Wolfgang Janni, Esther M. John, Audrey Jung, Rudolf Kaaks, Machteld Keupers, Cari M. Kitahara, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, James V. Lacey, Diether Lambrechts, Loı̈c Le Marchand, Annika Lindblom, Martha S. Linet, Robert Luben, Jan Lubiński, Michael Lush, Graham J. Mann, Mehdi Manoochehri, Sara Margolin, John W.M. Martens, Marı́a Elena Martı́nez, Dimitrios Mavroudis, Kyriaki Michailidou, Roger L. Milne, Anna Marie Mulligan, Taru Muranen, Heli Nevanlinna, William G. Newman, Sune F. Nielsen, Børge G. Nordestgaard, Andrew F. Olshan, Håkan Olsson, Nick Orr, Tjoung‐Won Park‐Simon, Alpa V. Patel, Bernard Peissel, Paolo Peterlongo, Dijana Plaseska‐Karanfilska, Karolina Prajzendanc, Ross L. Prentice, Nadège Presneau, Brigitte Rack, Gad Rennert, Hedy S. Rennert, Valerie Rhenius, Atocha Romero, Rebecca Roylance, Matthias Ruebner, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Andreas Schneeweiß, Christopher G. Scott, Mitul Shah, Snezhana Smichkoska, Melissa C. Southey, Jennifer Stone, Harald Surowy, Anthony J. Swerdlow, Rulla M. Tamimi, William Tapper, Lauren R. Teras, Mary Beth Terry, Rob A.�E.�M. Tollenaar, Ian Tomlinson, Melissa A. Troester, Thérèse Truong, Celine M. Vachon, Qin Wang, Amber N. Hurson, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, Hiltrud Brauch, Montserrat García‐Closas, Paul D.P. Pharoah, Douglas F. Easton, Georgia Chenevix‐Trench, Marjanka K. Schmidt

Bibliographic record

VenueUWA Profiles and Research Repository (UWA) · 2021
Typedataset
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsUniversity Health NetworkLunenfeld-Tanenbaum Research InstituteUniversity of Toronto
Fundersnot available
KeywordsGermlineBreast cancerPathologicalOncologyBiologyInternal medicineMedicineCancerGeneticsGene

Abstract

fetched live from OpenAlex

Additional file 1: Supplementary Table S1, Supplementary Table S2, Supplementary Table S3, and Supplementary Table S4. Supplementary Table S1. Shows an overview of the Breast Cancer Association Consortium studies included in the analyses. Supplementary Table S2. Includes the rationale and references to the literature supporting the choice of each subgroup for inclusion in a genome-wide association study on breast cancer-specific survival. Supplementary Table S3. Shows the characteristics of the breast cancer patients included in the 15-year breast cancer-specific survival analyses, overall and by subgroup. Supplementary Table S4. Shows the characteristics of the breast cancer patients included in the 5-year breast cancer-specific survival analyses for subgroups defined based on type of systemic treatment received.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.021
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.534
Threshold uncertainty score0.665

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.021
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.004
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.5340.072

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.307
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

Explore more

Same venueUWA Profiles and Research Repository (UWA)→Same topicBRCA gene mutations in cancer→French-language works237,207→