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Record W4394428291 · doi:10.6084/m9.figshare.8088503

Long non-coding RNA NEAT1 promotes steatosis via enhancement of estrogen receptor alpha-mediated AQP7 expression in HepG2 cells

2019· dataset· en· W4394428291 on OpenAlexaff
Xiaohua Fu, Jing Zhu, Lin Zhang, Jing Shu

Bibliographic record

VenueFigshare · 2019
Typedataset
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer-related molecular mechanisms research
Canadian institutionsUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsSteatosisEstrogen receptor alphaEstrogen receptorCancer researchEstrogenChemistryLong non-coding RNAAlpha (finance)Estrogen-related receptor alphaNon-coding RNACell biologyRNABiologyInternal medicineEndocrinologyMedicineBiochemistryGeneCancerBreast cancer

Abstract

fetched live from OpenAlex

We, the Editors and Publisher of Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article: Fu, X., Zhu, J., Zhang, L., & Shu, J. (2019). Long non-coding RNA NEAT1 promotes steatosis via enhancement of estrogen receptor alpha-mediated AQP7 expression in HepG2 cells. Artificial Cells, Nanomedicine, and Biotechnology, 47(1), 1782–1787. https://doi.org/10.1080/21691401.2019.1604536 Since publication, concerns were identified regarding the image integrity of Western Blot Figures 1C, RNA ­pulldown assay 3B, and the PCR methodology described in the article. When approached for an explanation, the authors responded, however, they were unable to address the concerns raised. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore ­retracting the article. The authors do not agree with the retraction. We have been informed in our decision-making by our editorial policies and the COPE guidelines. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.031
Threshold uncertainty score0.105

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0310.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.277
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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