MétaCan
Menu
Back to cohort
Record W4394486561 · doi:10.6084/m9.figshare.22601786

Additional file 10 of Single-cell transcriptomics highlights immunological dysregulations of monocytes in the pathobiology of COPD

2023· dataset· en· W4394486561 on OpenAlexaff
Qiqing Huang, Yuanyuan Wang, Lili Zhang, Wei Qian, Shaoran Shen, Jingshen Wang, Shuangshuang Wu, Wei Xu, Bo Chen, Mingyan Lin, Jianqing Wu

Bibliographic record

VenueFigshare · 2023
Typedataset
Languageen
FieldImmunology and Microbiology
TopicImmune cells in cancer
Canadian institutionsPrincess Margaret Cancer CentreUniversity of Toronto
Fundersnot available
KeywordsCOPDTranscriptomeMonocyteCellImmunologyMicrobiologyComputational biologyMedicineBiologyComputer scienceGeneticsGeneGene expressionInternal medicine

Abstract

fetched live from OpenAlex

Additional file 10: Dataset 8. Lists of markers in 2 sub-clusters of club cells, namely autoimmune-prone sub-cluster of club cells and mix sub-cluster of club cells, related to Fig. 5D and Fig. S5M. The resulting sub-cluster markers were identified by the seurat FindAllMarkers, including the p-value, the average log2(fold change) of the gene in the sub-cluster compared to all other sub-clusters, the percent of cells expressing the gene in the sub-cluster (pct.1), the percent of cells expressing the gene in all other sub-clusters (pct.2), and the adjusted p-value.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.376
Threshold uncertainty score0.890

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.013
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0030.001
Open science0.0020.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.3760.099

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.239
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueFigshareSame topicImmune cells in cancerFrench-language works237,207