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Efficacy of Qingshuanglu Exposure Combined with Oral Administration of Diosmin for Burn Scar Improvement and its Effect on Serum Levels of Pro-Inflammatory Factors

2024· article· en· W4394719625 on OpenAlexaboutno aff
Jun Chen, Jianbin Chen

Bibliographic record

VenueIndian Journal of Pharmaceutical Sciences · 2024
Typearticle
Languageen
FieldMedicine
TopicWound Healing and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsDiosminMedicinePharmacologyPathology

Abstract

fetched live from OpenAlex

To analyze the efficacy of Qingshuanglu in improving burn scars. First, 120 burn individuals were recruited and all the participants were given oral administration of diosmin and then randomized to Meibao Shi Run Shao Shang Gao and Qingshuanglu. Efficacy, visual analogue scale, vancouver scar scale score, pigmentation rate, wound drying time, healing time, safety, and serum inflammatory factor levels were comparatively analyzed. Patients receiving Qingshuanglu treatment showed shorter wound drying and healing time, lower visual analogue score, vancouver scar score, reduced pigmentation rate and total incidence of adverse reactions than those treated with Meibao. Moreover, markedly decreased levels of various serum inflammatory factors were observed in patients receiving Qingshuanglu, lower than the pre-treatment levels and those receiving Meibao. The study demonstrates that Qingshuanglu exposure could effectively repair burn injury, attenuate the inflammatory response, and reduce the scar formation for burn patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.514
Threshold uncertainty score0.262

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.394
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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