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CORRELATION OF THE S100B PROTEIN AND THE DEGREE OF COGNITIVE IMPAIRMENTS IN PATIENTS WITH HIV INFECTION

2023· article· en· W4394722376 on OpenAlexaboutno aff
В. З. Мовсумов, Л. П. Смертина

Bibliographic record

VenueVestnik SurGU Meditsina · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicS100 Proteins and Annexins
Canadian institutionsnot available
Fundersnot available
KeywordsHuman immunodeficiency virus (HIV)CognitionCognitive impairmentCorrelationMontreal Cognitive AssessmentMedicineCognitive declineS100 proteinPsychologyAudiologyImmunologyClinical psychologyInternal medicineDiseasePsychiatryDementia

Abstract

fetched live from OpenAlex

The study aims to investigate the relation between cognitive impairments and neurospecific S100β protein in HIV patients. The quantitative content of the neurospecific S100β protein in the blood of 20 patients with HIV infection was determined using the Montreal scale (MoCa test). In all cases, HIV patients with cognitive impairment had an elevated level of S100β, while in some cases, patients with an increased level of the S100β protein did not suffer from cognitive decline. S100β may be a marker of central nervous system damage causing cognitive decline, but it is not clear whether elevated levels of S100β can be a predictor of future cognitive deficiency.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.211
Teacher spread0.202 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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