Author Correction: IL-8 is a novel prometastatic chemokine in intrahepatic cholangiocarcinoma that induces CXCR2-PI3K/AKT signaling upon CD97 activation
Bibliographic record
Abstract
The original version of this Article contained an error in Figure 3 where the siNC group and IL-8+siNC group in panel (c) were misused. Figure 3 c was a duplication of the NC group and IL-8+NC group in Figure 4 panel (c). The original Figure 3 and accompanying legend appear below. Figure 3 IL-8 activates the PI3K/AKT pathway through CXCR2 (not CXCR1) to upregulate CD97 expression and promote EMT in ICC cells. Wound healing assays ( A , B ) and transwell migration assays ( C , D ) were performed to evaluate the migration of QBC-939 and RBE cells transfected with si-CXCR1, si-CXCR2 or si-NC after IL-8 or solvent treatment. The expression levels of CD97 and EMT-associated proteins, E-cadherin, N-cadherin, vimentin and PI3K/AKT pathway-associated proteins, PI3K, p-PI3K, AKT, and p-AKT in QBC-939 and RBE cells transfected with si-CXCR1, si-CXCR2 or si-NC after IL-8 or solvent treatment were determined by WB ( E , F ). * P < 0.05, ** P < 0.01, *** P < 0.001, # P > 0.05. si, small interfering; NC, negative control. Full size image
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.026 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.004 | 0.006 |
| Insufficient payload (model declined to judge) | 0.034 | 0.019 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".