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Record W4394826400 · doi:10.5376/amb.2024.14.0006

Whole-Genome Association Analysis in Revealing the Application of Genetic Factors Affecting Livestock Production Traits

2024· article· en· W4394826400 on OpenAlexvenueno aff
Siping Zhang, Xiaofang Lin

Bibliographic record

VenueAnimal Molecular Breeding · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsnot available
Fundersnot available
KeywordsLivestockGenome-wide association studyGenetic associationBiologyGenomeGenetic analysisBiotechnologyProduction (economics)GenomicsQuantitative trait locusComputational biologyGeneticsGeneSingle-nucleotide polymorphismGenotypeEcology

Abstract

fetched live from OpenAlex

This study reviews the application of whole-genome association analysis in revealing genetic factors affecting livestock production traits. With the continuous development of biotechnology and genomics, whole-genome association analysis has gradually received attention as a powerful genetic research tool. This method detects associations between a large number of genetic markers and traits of interest, revealing the genetic basis of livestock production traits and providing a scientific basis for breeding and genetic improvement. This study first introduces the definition and classification of livestock production traits, as well as their genetic background and influencing factors. Next, an overview of the principles and methods of whole-genome association analysis is provided, along with a comparison of the advantages and disadvantages of traditional genetic research methods and whole-genome association analysis. Subsequently, through typical case analysis, the application and technological progress of whole-genome association analysis in the study of livestock production traits are elaborated in detail. Further discussion includes key genes and genetic markers identified through this method, as well as their practical applications in livestock genetic improvement. Finally, the importance of whole-genome association analysis in deciphering the genetic basis of livestock production traits is summarized, and the potential application value of it in the sustainable development of animal husbandry is discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.915
Threshold uncertainty score0.554

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.246
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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