MétaCan
Menu
Back to cohort
Record W4394875575 · doi:10.1016/j.isci.2024.109761

OlCHR, encoding a chromatin remodeling factor, is a killer causing hybrid sterility between rice species Oryza sativa and O. longistaminata

2024· article· en· W4394875575 on OpenAlexfundno aff
Zin Mar Myint, Yohei Koide, Wakana Takanishi, Tomohito Ikegaya, Choi Kwan, Kiwamu Hikichi, Yoshiki Tokuyama, Shuhei Okada, Kazumitsu Onishi, Ryo Ishikawa, Daisuke Fujita, Yoshiyuki Yamagata, Hideo Matsumura, Yuji Kishima, Akira Kanazawa

Bibliographic record

VenueiScience · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Mapping and Diversity in Plants and Animals
Canadian institutionsnot available
FundersHokkaido UniversityInstitute of GeneticsNational Institute of GeneticsJapan Society for the Promotion of ScienceMinistry of Education, Culture, Sports, Science and TechnologyResearch Organization of Information and SystemsJapan Agency for Medical Research and Development
KeywordsOryza sativaBiologySterilityChromatin remodelingIsolation (microbiology)BotanyReproductive isolationOryzaChromatinGeneGeneticsBioinformaticsMedicine

Abstract

fetched live from OpenAlex

The genetic mechanisms of reproductive isolation have been widely investigated within Asian cultivated rice ( Oryza sativa ); however, relevant genes between diverged species have been in sighted rather less. Herein, a gene showing selfish behavior was discovered in hybrids between the distantly related rice species Oryza longistaminata and O. sativa . The selfish allele S13 l in the S13 locus impaired male fertility, discriminately eliminating pollens containing the allele S13 s from O. sativa in heterozygotes ( S13 s / S13 l ). Genetic analysis revealed that a gene encoding a chromatin-remodeling factor (CHR) is involved in this phenomenon and a variety of O. sativa owns the truncated gene OsCHR745 , whereas its homologue OlCHR has a complete structure in O. longistaminata . CRISPR-Cas9-mediated loss of function mutants restored fertility in hybrids. African cultivated rice, which naturally lacks the OlCHR homologue, is compatible with both S13 s and S13 l carriers. These results suggest that OlCHR is a Killer gene, which leads to reproductive isolation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.541
Threshold uncertainty score0.453

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.269
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueiScienceSame topicGenetic Mapping and Diversity in Plants and AnimalsFrench-language works237,207