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Record W4394951092 · doi:10.21203/rs.3.rs-4223910/v1

Agreement and predictive value of the Clinical Frailty Scale in hospitalised older patients

2024· preprint· en· W4394951092 on OpenAlexaff
Liese Lanckmans, Olga Theou, Nele Van Den Noortgate, Ruth Piers

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsDalhousie University
Fundersnot available
KeywordsPredictive valueScale (ratio)Value (mathematics)MedicineGerontologyStatisticsInternal medicineMathematicsGeographyCartography

Abstract

fetched live from OpenAlex

Abstract Purpose: Our objective was to determine the agreement of the Clinical Frailty Scale (CFS) by comparing scores obtained by a senior geriatrician, a junior geriatrician, and by using a classification tree. Additionally, we evaluated the predictive value of the CFS for 6-month mortality after admission to an acute geriatric unit. Methods: This prospective study was conducted in two acute geriatric units in Belgium. The premorbid CFS was determined by senior and junior geriatricians based on clinical judgement. Another junior geriatrician, who did not have a treatment relationship with the patient, scored the CFS using the classification tree. Intraclass correlation coefficient (ICC) was calculated to assess agreement. A ROC curve and Cox regression model determined prognostic value. Results: In total, 97 patients with a mean age of 86 years (SD 5.2) were included. The reliability of the CFS, when determined by the senior geriatrician and the classification tree, was moderate (ICC 0.526, 95% CI [0.366-0.656]). This is similar to the agreement between the senior and junior geriatricians’ CFS (ICC 0.643, 95% CI [0.510-0.746]). The AUC for 6-month mortality based on the senior geriatrician’s CFS was 0.774. Cox regression analysis indicated that severe or very severe frailty was associated with a higher risk of mortality compared to mild or moderate frailty (hazard ratio 3.476, [1.531-7.888], p = 0.003). Conclusion: The CFS classification tree can help standardize CFS scoring, enhancing reliability when used by less experienced raters.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.019
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.433
Teacher spread0.369 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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