Cognitive deficits and coronary calcium levels in hypertension on the background of bronchial asthma
Bibliographic record
Abstract
Background. The article presents the results of a study to identify cognitive deficits in patients based on the level of coronary calcium with concomitant pathology in the form of hypertension and bronchial asthma. Currently, it is believed that a long-term increase in blood pressure, which does not have proper correction, leads to cognitive impairment. At the same time, bronchial asthma, in the absence of proper therapy, in the case of reduced adherence to treatment and as a result of the occurrence of chronic hypoxia of the brain, the disease affects cognitive functions. It has been repeatedly proven that an increase in the calcium index in combination with concomitant comorbidity worsens brain perfusion, which undoubtedly affects cognitive functions. Objective. The purpose of this study is to evaluate coronary calcium and cognitive deficits in comorbid patients with arterial hypertension and bronchial asthma. In the course of the work, 83 patients with comorbid conditions of hypertension and BA were examined, tested according to these scales and calculated the calcium index, which allowed us to obtain the following results. Results. The calcium index (Agaston index) in group I with (AH) 41.2 ± 32.1; in group II with AH and BA 91.0 ± 45.2, in group III conditionally healthy – 7.1 ± 2.1. The Montreal Cognitive Function Assessment Scale (MoSA) and the Short Mental Status Assessment Scale (MMSE) were used to assess the level and presence of initial cognitive impairment. According to the MoHS scale, patients with arterial hypertension scored 27.4 ± 1.7 points. The group of patients with bronchial asthma in combination with arterial hypertension scored an average of 26.5 ± 1.6 points, the control group scored 28.1 ± 1.4 points. According to the MMSE scale: in group I, patients with arterial hypertension received 28.7 ± 0.9 according to the results of the survey; in group II with a combination of arterial hypertension and bronchial asthma – 28.1 ± 1.2 points, in group III conditionally healthy patients – 29.3 ± 0.8 points.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".