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Record W4394995052 · doi:10.21203/rs.3.rs-4279440/v1

Sero-prevalence and risk factors of hepatitis B virus infection among pregnant women attending antenatal clinics in Adigrat General Hospital, Eastern Tigrai, Northern Ethiopia

2024· preprint· en· W4394995052 on OpenAlexaff
Getachew Kahsu Abay, Aderajew Gebrewahd, Brhane Berhe, Getachew Belay, Birhane Tesfanchal, Tsega Kahsay, Berhane Fseha, Senait Tadesse, Mulugeta Birhane, Mulualem Gebre, Pammla Petrucka

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicHepatitis B Virus Studies
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsMedicineObstetricsHepatitis B virusEnvironmental healthPregnancyFamily medicinePediatricsVirologyVirusBiology

Abstract

fetched live from OpenAlex

Abstract OBJECTIVES Hepatitis B virus (HBV) infection is one of the most common health problems, causing high mortality and heavy economic burden worldwide. The aim of this study was to determine the sero-prevalence of hepatitis B surface antigen (HbsAg) and associated risk factors among pregnant women attending antenatal clinics in Adigrat General Hospital Northern Ethiopia. METHODS Institutional based cross-sectional study was conducted from January to March, 2024 among 385 pregnant women. Participants were selected through systematic random sampling method. Socio demographic and associated factors data were collected using a structured questionnaire and 5 milliliter blood sample was collected. The data were entered to EPI Info and analyzed using SPSS version 25. Descriptive statistics were computed. Bivariate and multi-variant regression analysis was employed to measure the association values < 0.05 were considered statistically significant. RESULTS The overall sero-prevalence of HBsAg among the 385 study subjects enrolled was 10.4% (n = 40). HBsAg was common in all age groups. The infection was higher those who had history of multiple sexual partner (22.7%),ear-piercing (13.4%), history of abortion (27.6%), history of delivery (26.3%) and history of genital mutilation (35.7%).In multivariate logistic regression being unmarried (AOR 8.57; 95% CI 3.20-22.93) ,being illiterate (AOR 12.06; 95% CI 3.07–47.33) ,history of ear piercing (AOR 5.66; 95% CI 1.65–19.45), history of abortion (AOR 8.16; 95% CI 3.18–20.95), history of home delivery (AOR 6.69; 95% CI 1.26–35.53) and history of genital mutilation (AOR 9.77; 95% CI 2.64–36.18) of acquiring HBV infection compared to their counterparts. CONCLUSIONS The result showed that HBV was highly prevalent in our study area. Being unmarried, Low educational level, ear piercing, abortion, home delivery and genital mutilation were significantly associated with HBV infection. Therefore, this finding suggests that health education programs should be given to the community to raise the awareness of mothers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.372
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractyes

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