MétaCan
Menu
Back to cohort
Record W4395022890 · doi:10.1093/jtm/taae065

A randomized controlled trial of two hepatitis A vaccine doses among adolescents with juvenile idiopathic arthritis and Crohn’s disease on immunosuppressive therapy: a pilot study

2024· article· en· W4395022890 on OpenAlexaff
Racheal Githumbi, Susan Kuhn, Carla Osiowy, Jacqueline Day, Jennifer deBruyn, Marvin J. Fritzler, Nicole Johnson, Otto G. Vanderkooi, Heinrike Schmeling

Bibliographic record

VenueJournal of Travel Medicine · 2024
Typearticle
Languageen
FieldMedicine
TopicHepatitis Viruses Studies and Epidemiology
Canadian institutionsPublic Health Agency of CanadaUniversity of Calgary
Fundersnot available
KeywordsMedicineImmunogenicityRandomized controlled trialJuvenileHepatitis A vaccineArthritisDiseaseImmunologyHepatitisInternal medicineAntibody

Abstract

fetched live from OpenAlex

This pilot randomized controlled trial assessed the immunogenicity of paediatric vs adult hepatitis A vaccine doses in immunosuppressed adolescents (12–15 years) with juvenile idiopathic arthritis and Crohn’s disease. The study aimed to assess if a single, higher dose provides better immunogenicity, particularly before travel.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.157
Threshold uncertainty score0.760

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0050.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.314
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Travel MedicineSame topicHepatitis Viruses Studies and EpidemiologyFrench-language works237,207