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Record W4395059583 · doi:10.5206/uwomj.v89i2.10963

A Biological Caste System? An Investigation of Epigenetics and Socioeconomic Status in Western Society

2021· article· en· W4395059583 on OpenAlexvenueno aff
Dalton Ruel

Bibliographic record

VenueUniversity of Western Ontario Medical Journal · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRace, Genetics, and Society
Canadian institutionsnot available
Fundersnot available
KeywordsCasteSocioeconomic statusEpigeneticsSociologySocioeconomicsBiologyDemographyPolitical scienceGeneticsPopulation

Abstract

fetched live from OpenAlex

Epigenetic research has revealed that socioeconomic status (SES) affects people’s lives much more than previously thought. Studies have previously found links between SES and health outcomes that could not be explained by factors classically attributed to the phenomenon of health disparities between the rich and the poor. Further research suggests that epigenetic markers that correlate with SES can have physiologic effects on the individual carrying them, including risk for cardiovascular disease and depression. These markers modulate gene expression without altering the genetic code and are typically regulated by the environment in which an individual or their ancestors lived. Current findings highlight the importance of putting medical care in the context of patient experience, but this research only scratches the surface of the association between SES-related changes in the epigenome and social mobility. Future studies can further investigate if stressors related to low SES are driving epigenetic changes that affect health outcomes. This relationship may have societal consequences and could shape the future of medicine by influencing policy making and personalized patient care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.055
Threshold uncertainty score0.960

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.217
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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