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Record W4395098342 · doi:10.5376/rgg.2024.15.0002

Development of CRISPR-Cas9 Multiple Editing System for Genetic Improvement of Rice

2024· article· en· W4395098342 on OpenAlex
Yu Wang

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueRice Genomics and Genetics · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCRISPR and Genetic Engineering
Canadian institutionsnot available
Fundersnot available
KeywordsCRISPRGenome editingBiologyCas9BiotechnologyComputer scienceComputational biologyGeneticsGene

Abstract

fetched live from OpenAlex

The CRISPR-Cas9 multiple editing system has become an important tool in the field of rice genetic improvement. This review aims to outline the principles and applications of the system, emphasizing its cutting-edge position in rice breeding. The advantage of a multiple editing system is that it can simultaneously edit multiple loci to achieve precise improvement of rice yield, resistance, and quality traits. This review also discusses in detail the working principle, development process, and widespread application of multiple editing systems, briefly introduces CRISPR-Cas9 technology, explains how multiple editing systems can achieve efficient multi gene editing, and delves into the specific applications of multiple editing systems in rice genetic improvement, including increasing yield, increasing resistance, and improving quality. These applications have enriched the genetic resources of rice and provided new avenues for food security and sustainable agricultural development.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.113
Threshold uncertainty score0.729

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.262
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it