PSIII-21 Impact of high zinc oxide supplementation or lignocellulose supplement on chronic markers of intestinal inflammation and growth of weaned piglets
Bibliographic record
Abstract
Abstract The objective of this project was to study the effects of high zinc oxide (ZO) supplementation and fiber supplement from lignocellulose (LIGCEL) on chronic markers of intestinal inflammation and growth of weaned piglets. At weaning (21 d), 150 piglets (body weight = 6.39 ± 0.276 kg) were transferred from a farrowing farm to a nursery farm where they were divided into 30 pens of 5 piglets per pen according to their weanling weight. Each pen was assigned to one of the following three treatments: Control (CON, 150 mg/kg of zinc), ZO (2,500 mg/kg of zinc), and LIGCEL (CON+3% lignocellulose). The ZO and LIGCEL supplements were added to a phase 1 diet. The experimental diets (phase 1) were distributed for 14 d. Subsequently, all piglets received the same diets from phases 2 and 3 for two periods of 14 d. During the experiment, piglets were weighed upon arrival and after phases 1, 2, and 3. The feed was distributed every day and the total quantities calculated for each of the feeding phases. The average daily gain (ADG), average daily feed intake (ADFI) and feed conversion (FC) were subsequently calculated (Table 1). On d 6 and 13, the blood of two piglets per pen was collected to determine the content of D-lactate and diamine oxidase (DAO). Fecal samples from these two piglets were also taken to evaluate the calprotectin and neopterin contents. During phase 1, ADG was greater for ZO piglets compared with the CON animals with an intermediate value for the LIGCEL group (P < 0.001). The ADFI was greater for the ZO compared with the CON and LIGCEL treatments (P < 0.003). Piglets in the ZO and LIGNOCELL treatments had less FC than those in the CON group (P < 0.001). During phase 2, only the FC was greater for the ZO and LIGCEL treatments compared with CON animals (P < 0.013). During phase 3, growth performances were not affected by the dietary treatments. For the entire experiment, ZO piglets had greater ADG than those in the CON group with an intermediate value for LIGCEL treatment (P < 0.019). D-lactate decreased from d 6 to 13 while DAO increased (P < 0.001). The DAO was also greater for ZO and LIGCELL piglets compared with CON animals (P < 0.001). Neopterin was greater for ZO treatment but only on d 13 (Trt × day, P < 0.010). Finally, calprotectin decreased from d 6 to 13 (P < 0.001) but was not affected by dietary treatments. In conclusion, ZO and LIGCEL fiber act positively on growth by modulating markers of intestinal inflammation. LIGCEL fiber could, therefore, be an alternative to ZO in the diet of weaned piglets.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".