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Record W4396655634 · doi:10.1101/2024.05.03.24306818

SCORE: Serologic Evidence of COVID-19, Social, and Occupational Contacts in Healthcare Workers in a Sample of Long-Term Care and Acute Care Facilities in Southeastern Ontario (SCORE)

2024· preprint· en· W4396655634 on OpenAlexaffabout
Jorge Martínez-Cajas, Beatriz Alvarado, Ann Jolly, Yanping Gong, Bradley P. Stoner, T. Hugh Guan

Bibliographic record

VenuemedRxiv · 2024
Typepreprint
Languageen
FieldMedicine
TopicInfection Control and Ventilation
Canadian institutionsOttawa Public HealthKingston Health Sciences CentreQueen's University
Fundersnot available
KeywordsSample (material)MedicineHealth careCoronavirus disease 2019 (COVID-19)Long-term careEnvironmental healthAcute careSerologyNursingInternal medicineEconomic growthEconomicsDisease

Abstract

fetched live from OpenAlex

ABSTRACT Purpose Healthcare workers (HCW) have been an essential societal resource to face the COVID-19 pandemic. Early in the pandemic, they were at increased risk of contracting SARS-CoV-2 infection. We established a longitudinal cohort of HCW in an acute care hospital and four long-term care facilities in Ontario, Canada to follow the incidence of SARS-CoV-2 infection, the immune response to infection and/or vaccination, and the occupational, household and community factors related to their risk of infection. Participants Two hundred participants were recruited between November 2020 and July 2021. They completed a baseline survey, monthly surveillance data for 9-12 months, a post-Omicron-wave survey, and provided blood samples for anti-SARS-CoV2 antibody measurements. We collected data on host-related factors (humoral response to vaccines and SARS-CoV-2 infection) and environmental factors (social contact history, occupational, household and community conditions) to establish the main determinants of risk of SARS-CoV-2 infection. Findings Here, we describe the cohort demographics, occupational characteristics, SARS-CoV-2 vaccination status and COVID-19 infection risk during the cohort follow-up. Analyses The data from this cohort of HCW allows analyses on 1) the risk factors for SARS-CoV-2 infection, 2) the impact of the Omicron variant on the risk of infection; 3) the relationship between humoral responses and SARS-CoV-2 infection/vaccination and, 4) their relationship of SARS-CoV-2 infection and the community, household and healthcare facility-related exposures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.140
Threshold uncertainty score0.281

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.362
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes2
Has abstractyes

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