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Development of an mRNA-based therapeutic vaccine mHTV-03E2 for high-risk HPV-related malignancies

2024· article· en· 27 citations· W4396668167 on OpenAlex· 10.1016/j.ymthe.2024.04.036

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Development of an mRNA therapeutic vaccine for HPV-related malignancies; the object is a vaccine.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

It concerns development of a therapeutic cancer vaccine, not research practice.

Grok 4.5OUT
genre: other
about Canada: no
confidence: high

Therapeutic HPV mRNA vaccine development; biomedical product research, not metaresearch.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Molecular Therapy
Topic
Immunotherapy and Immune Responses
Field
Immunology and Microbiology
Canadian institutions
Biotechnology Research Institute
Funders
Chinese Academy of Medical Sciences Initiative for Innovative MedicineNational Natural Science Foundation of ChinaNational Medical Research CouncilChinese Academy of Meteorological SciencesChinese Academy of SciencesInstitute of Biophysics, Chinese Academy of Sciences
Keywords
Immune systemAntigenImmunityVaccinationImmunologyCD8Cancer researchMedicineBiology
Has abstract in OpenAlex
no