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Application of antimicrobial nanocoatings on biological implants

2024· article· en· W4396672111 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueApplied and Computational Engineering · 2024
Typearticle
Languageen
FieldEngineering
TopicBone Tissue Engineering Materials
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsAntimicrobialNanotechnologyMaterials scienceCoatingNanomaterialsBiofilmBiocompatibilitySurface modificationAntibioticsImplantBiomedical engineeringMedicineMicrobiologyBacteriaEngineeringBiologySurgeryMechanical engineering

Abstract

fetched live from OpenAlex

Implant infections have become a major obstacle to implant failure. Although traditional antibiotic treatments have provided a solution to some extent, conventional antibiotic drug treatments fail to eradicate bacteria and even cause antibiotic resistance. Therefore, the development of biomedical implants employing antimicrobial coatings becomes the focus of more and more research. Nanomaterials, with their excellent biocompatibility and unique antimicrobial properties, have been widely used in biomedical devices. This paper focuses on the application of nanocoatings in biomedical implants and the introduction of potential surface functionalization materials for implants. This paper will analyze metals as well as their oxide nanoparticles and 2d-nanomaterial-based Nanocoatings with antimicrobial properties. It is also essential to highlight how these nanoparticles can deal with biofilm infections and achieve antimicrobial properties. In addition, the article describes different nanoparticle coating strategies that provide a variety of options for the design of antimicrobial coatings for implants. In conclusion, nanotechnology provides clues to solve the problem of biomedical implant infections, reduces the risk of infection, and generates more reliable and effective treatments for patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.344
Threshold uncertainty score0.512

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.193
Teacher spread0.187 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it