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Record W4396989374 · doi:10.1681/asn.20223311s1274c

Prediction Model for 6-Month Mortality in Incident Older Hemodialysis Patients: Data From the Korean Society of Geriatric Nephrology

2022· article· en· W4396989374 on OpenAlexaboutno aff
Woo Yeong Park, Jang‐Hee Cho, Byung Chul Yu, Miyeun Han, Sang Heon Song, Gang-Jee Ko, Jae Won Yang, Sung Jin Chung, Yu Ah Hong, Young Youl Hyun, Eunjin Bae, In O Sun, Hyunsuk Kim, Won Min Hwang, Sung Joon Shin, Soon Hyo Kwon, Kyung Don Yoo

Bibliographic record

VenueJournal of the American Society of Nephrology · 2022
Typearticle
Languageen
FieldMedicine
TopicDiverse Approaches in Healthcare and Education Studies
Canadian institutionsnot available
Fundersnot available
KeywordsNephrologyHemodialysisMedicineInternal medicineIntensive care medicineGerontology

Abstract

fetched live from OpenAlex

Background: Early mortality following hemodialysis initiation is a barrier to improving patient survival. We aimed to develop a clinical risk model to predict the early mortality of older hemodialysis patients. Methods: Hemodialysis patients aged >70 years were recruited from a retrospective cohort from the Korean Society of Geriatric Nephrology (KSGN). A prognostic score for 6-month mortality risk after dialysis initiation was developed, named the KSGN score. Multivariate Cox regression analysis was used to select risk factors from 20 clinical variables. β-coefficients were converted to natural logarithms for the final risk score model. Results: Among the 1,967 incident hemodialysis patients, the crude 6-month mortality rate was 15.7% (n=309). In the multivariate Cox analysis, independent risk factors for 6-month mortality and each score were as follows: the body mass index (<18.5 kg/m2 (0), 18.5≤, <23 kg/m2 (0)), age at dialysis initiation (<80 years (0), ≥85 years (1)), status of malignancy (curative state (0), palliative treatment (1)), hypertension (0), nursing hospital care at dialysis initiation (0), vascular access at dialysis initiation (arteriovenous graft (-1)), vascular access on maintenance dialysis (arteriovenous fistula (-1), arteriovenous graft (-1)), and serum albumin (0)). According to the KSGN score, mortality rate was 4.8%, 8.6%, 32.0%, 60.3%, and 66.7% for -2, -1, 0, 1, and 2 points, respectively. The area under the curve of the KSGN score was significantly higher than that of either the Alberta or United States Renal Data System scores. Conclusions: The KSGN score is a simple tool to predict early mortality after dialysis initiation in older patients with end-stage kidney disease and may be useful to support decision-making and management in older adults starting dialysis.Comparison of ROC curve between the prognostic models

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.100
GPT teacher head0.343
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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Same venueJournal of the American Society of NephrologySame topicDiverse Approaches in Healthcare and Education StudiesFrench-language works237,207