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Does acute heat stress alter lactation performance in postpartum mothers?

2024· article· en· W4398175937 on OpenAlexaffabout
KarLee Lefebvre, Yasamin Razi, Taryn Klarner, Ian Newhouse, Nicholas Ravanelli

Bibliographic record

VenuePhysiology · 2024
Typearticle
Languageen
FieldMedicine
TopicBirth, Development, and Health
Canadian institutionsLakehead University
Fundersnot available
KeywordsLactationHeat stressStress (linguistics)MedicineInternal medicineEndocrinologyBiologyAnimal sciencePregnancyGenetics

Abstract

fetched live from OpenAlex

Introduction: Heat stress has been shown to acutely decrease lactation performance in various mammalian species, however whether a similar effect is present in humans remains largely unexplored. Objective and hypothesis: The objective of the present study was to determine whether an acute whole-body heat stress reduces lactation performance in postpartum mothers in the proceeding 24 h. Methods: To date, 9 postpartum mothers (32±4 y; 1.6 ±0.1 m; 67±13 kg; 8±3 months postpartum) have participated in the study. During the 24 h period before and after the acute passive heat stress, participants were asked to record their voluntary fluid intake and their milk production defined as the volume of expressed milk and/or breastfeeding volume based on the baby’s weight before and immediately after nursing, accounting for evaporative water losses. The passive heat stress protocol involved participants laying supine while donning a tube-lined garment continuously perfused with 49°C water for 60 minutes. Rectal temperature and heart rate were measured during the passive heat stress intervention to confirm thermal strain, and whole-body sweat losses were calculated as the net difference in body mass following passive heat stress. Results: The 60-minute passive heat stress protocol increased rectal temperature by 0.4±0.3°C, increased heart rate (17±12 BPM), and resulted in a whole-body sweat loss of 278±201 g. The frequency of lactation was similar during the 24 h before (5.4±1.6 times) and 24 h after (5.1±1.1 times, P=0.20) acute passive heat stress. The total volume of human milk production in the 24 h prior to heat stress was not different to the 24 h following heat stress (pre: 327±123 ml, post: 312±148 ml, P=0.33). Maternal fluid intake was higher during the 24 h after passive heat stress (1561±73 ml) in comparison to the 24 h before (1377±244 ml, P=0.05). Conclusion: Preliminary data suggests that an acute bout of whole-body heat stress does not modulate lactation performance in postpartum mothers. This research was supported by Dr. Ravanelli’s Natural Sciences and Engineering Research Council of Canada Discovery Grant (PIN#2022-05096). This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.721
Threshold uncertainty score0.199

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.302
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes2
Has abstractyes

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