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Record W4399244028 · doi:10.1016/j.jpeds.2024.114132

Reference Ranges for Arterial Oxygen Saturation, Heart Rate, and Cerebral Oxygen Saturation during Immediate Postnatal Transition in Neonates Born Extremely or Very Preterm

2024· article· en· W4399244028 on OpenAlexafffund
Christina H. Wolfsberger, Bernhard Schwaberger, Berndt Urlesberger, Alexander Avian, Katharina Goeral, Marlene Hammerl, Tina Perme, Eugene Dempsey, Laila Springer, Gianluca Lista, Tomasz Szczapa, Hans Fuchs, Łukasz Karpiński, Jenny Bua, Brenda Hiu Yan Law, Julia Buchmayer, Ursula Kiechl‐Kohlendorfer, Lilijana Kornhauser-Cerar, Christoph E. Schwarz, Kerstin Gründler, Ilaria Stucchi, Katrin Klebermaß-Schrehof, Georg M. Schmölzer, Gerhard Pichler, Nariae Baik‐Schneditz, Marlies Bruckner, Corinna Binder‐Heschl, Christoph Schlatzer, Johann Martensen, Nina Höller, E Ziehenberger, Lukas P. Mileder, Angelika Berger, Sigrid Baumgartner, Agnes Grill, Michaela Mayr, Michael Schneider, Christina Schreiner, Elke Griesmaier, Vera Neubauer, Peter Wöckinger, Anna Posod, Anja Marolt, Ana Dimnik, Vlasta L Kurtovič, Garvey Aisling, Jurate Panaviene, David Healy, Ita Herlihy, Axel R. Franz, Francesca Castoldi, Francesco Cavigioli, Zuzanna Kozłowska, Marcin Minta, Zuzanna Owsiańska, Sonia Kahtan, Natalia Neumann- Klimasińska, Karolina Wróbel, Agata Kubiaczyk, Katarzyna Kosik, Katarzyna Olek, Michalina Bugiera, Julita Porwolik, Agnieszka Basiukajć, Elzbieta Czapla, Wojciech Łukaszuk, Katarzyna Gryczka, Dobrochna Naskręcka, Jan Mazela, Marta Szymankiewicz‐Bręborowicz, Daniel Klotz, Jana Baumgartner, Jana Bembich, Laura Travan, Po‐Yin Cheung

Bibliographic record

VenueThe Journal of Pediatrics · 2024
Typearticle
Languageen
FieldMedicine
TopicHemodynamic Monitoring and Therapy
Canadian institutionsRoyal Alexandra HospitalUniversity of Alberta
FundersHRB Clinical Research Facility GalwayStollery Children’s Hospital FoundationAustrian Science FundWomen and Children's Health Research Institute
KeywordsSaturation (graph theory)Oxygen saturationOxygenPercentileHeart rateAnesthesiaMedicineCardiologyInternal medicineBlood pressureChemistryMathematicsStatistics

Abstract

fetched live from OpenAlex

ObjectiveTo define percentile charts for arterial oxygen saturation (SpO2), heart rate (HR), and cerebral oxygen saturation (crSO2) during the first 15 minutes after birth in neonates born very or extremely preterm and with favorable outcome.Study designWe conducted a secondary-outcome analysis of preterm neonates included in the COSGOD III trial with visible cerebral oximetry measurements and with favorable outcome, defined as survival without cerebral injuries until term age. We excluded infants with inflammatory morbidities within the first week after birth. SpO2 was obtained by pulse oximetry, and electrocardiogram or pulse oximetry were used for measurement of HR. CrSO2 was assessed with near-infrared spectroscopy. Measurements were performed during the first 15 minutes after birth. Percentile charts (10th to 90th centile) were defined for each minute.ResultsA total of 207 preterm neonates with a gestational age of 29.7 (23.9-31.9) weeks and a birth weight of 1200 (378-2320) grams were eligible for analyses. The 10th percentile of SpO2 at minute two, five, ten and 15 was 32%, 52%, 83% and 85%, respectively. The 10th percentile of HR at minute two, five, ten and 15 was 70bpm, 109bpm, 126bpm and 134bpm, respectively. The 10th percentile of crSO2 at minute two, five, ten and 15 was 15%, 27%, 59% and 63%, respectively.ConclusionsThis study provides new centile charts for SpO2, HR, and crSO2 for extremely preterm neonates with favorable outcome. Implementing these centiles in guiding interventions during the stabilization process after birth might help to more accurately target oxygenation during postnatal transition period.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.912
Threshold uncertainty score0.356

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.273
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2024
Admission routes2
Has abstractyes

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