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Record W4399304292 · doi:10.56083/rcv4n5-236

USO DE MEDICAMENTOS NO TRATAMENTO DA DOENÇA DE PARKINSON E IMPLICAÇÕES DE TRATAMENTOS ALTERNATIVOS

2024· article· pt· W4399304292 on OpenAlexaff
João Gomes Pontes Neto

Bibliographic record

VenueRevista Contemporânea · 2024
Typearticle
Languagept
FieldMedicine
TopicNeurological disorders and treatments
Canadian institutionsEncana (Canada)
Fundersnot available
KeywordsMedicineParkinson's diseaseInternal medicineDisease

Abstract

fetched live from OpenAlex

O presente estudo tem como objetivo primordial disseminar conhecimentos sobre a doença de Parkinson e as implicações dos poucos medicamentos atualmente disponíveis para seu tratamento. Há indícios de escassez de investimentos em novas pesquisas de tratamentos farmacológicos e a falta de atenção voltada para as necessidades dos pacientes afetados por essa doença neurodegenerativa. Ao abordar o Parkinson, é fundamental compreender todas as formas de terapia disponíveis, considerando que a estabilização da condição ao longo do tempo requer não apenas tratamento farmacológico, mas também outras modalidades terapêuticas. O texto explorará algumas modalidades terapêuticas para o tratamento da Doença de Parkinson, examinando tanto seus aspectos favoráveis quanto desfavoráveis, bem como potenciais desafios relacionados à adesão aos medicamentos. O tratamento dessa enfermidade demanda cuidado minucioso e requer uma abordagem empática e atenciosa. A pesquisa de artigos seleciona publicações entre 2019 e 2023 na plataforma PubMed, utilizando descritores como: Parkinson disease, treatment of tremors, cannabinoids, levodopa e deep brain stimulation. Após aplicação de critérios de inclusão e exclusão, foram selecionados 9 estudos relevantes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.008
Threshold uncertainty score0.027

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0080.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.326
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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