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Record W4399442265 · doi:10.52711/2231-5691.2024.00011

The Next Pandemic

2024· article· en· W4399442265 on OpenAlex
Rehan Haider

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueAsian Journal of Pharmaceutical Research · 2024
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
Fundersnot available
KeywordsDementiaQuarter (Canadian coin)PandemicPopulationGerontologyMedicineIncidence (geometry)DemographyCoronavirus disease 2019 (COVID-19)GeographyDiseaseEnvironmental healthPathologySociologyInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

Dementia is a innovative and irreversible situation that represents a important mission to fitness and social care offerings round the world. An Alzheimer's Research fee file by using the college of Oxford in 2010 suggests that there are simply over 820,000 humans in the U.K. residing with dementia. This quantity is projected to upward shove to over 1 million via 2021 and over 1.7million through 2051, due to the Uk's getting old population. It is estimated that 670 zero household and buddies are appearing as most important carers The incidence of each early and late-onset dementia will increase with age has dementia, rising to 1in 6 human beings over 80 years and 1 in 3 of these aged over 75 years. It is greater frequent in a lady than in men. Over 17,000 younger humans (below the age of 65 years) in the UK have dementia. This is referred to as early-onset or young-onset dementia. An estimated two 0.33 of Care domestic residents have some shape of dementia however two 0.33 of all the human beings with dementia in the UK stay in the community. Approximately a quarter of Hospital beds are occupied through humans over the age of sixty five years with dementia. In 2010 the monetary fee of dementia to the NHS, nearby authorities, and households used to be 23 billion kilos per year. Greater than cancer(12 billion kilos per year) and coronary heart sickness (8 billion kilos per year) combined, and this is estimated to develop to 27 billion kilos by way of 2018. The term' dementia ' is used to describe a series of signs that may additionally encompass reminiscence loss, planning, problem-solving, language, communication, and reasoning difficulties alongside with adjustments in mood or behavior. There is regularly an related deterioration in the person's capability to lift out things to do of every day living. The most frequent kind of dementia money owed for about two to three instances and is barely greater frequent in ladies than men. The sickness is named after Dr. Alois Alzheimer's a German neurologist who described the Genius pathology of a 51years - historical female who died of a 'dementing type' sickness in 1907. The 'Amyloid cascade Hypothesis' has been proposed as the reason of AD through Klafki. et.al. This is based totally on proof that suggests that AD is related with a number types of extraordinary cloth inside the brain- neurofibrillary tangles and amyloid plaques, this impacts how nerve cells work and talk with every other, lowering the stage of chemical messengers and cells to die.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.933
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0070.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.259
GPT teacher head0.553
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it