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Record W4399442817 · doi:10.1101/2024.06.05.597607

How the Tulip Breaking Virus Creates Striped Tulips

2024· preprint· en· W4399442817 on OpenAlexaff
Aidan A. Wong, Gustavo Carrero, Thomas Hillen

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2024
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Virus Research Studies
Canadian institutionsAthabasca UniversityUniversity of Alberta
Fundersnot available
KeywordsArt

Abstract

fetched live from OpenAlex

Abstract The beauty of tulips has enchanted mankind for centuries. The striped variety has attracted particular attention for its intricate and unpredictable patterns. A good understanding of the mechanism that drives the striped pattern formation of the broken tulips has been missing since the 17th century. It is known since 1928 that these patterned tulips suffer from a viral infection by the tulip breaking virus . Here, we present a mathematical model to understand how a virus infection of the petals can lead to stripes, thereby solving a 350 year old mystery. The model, which describes the viral inhibition of pigment expression (anthocyanins) and their interaction with viral reproduction, incorporates a pattern formation mechanism identified as an activator-substrate mechanism, similar to the well-known Turing instability, working together with a Wolpert’s positional information mechanism. The model is solved on a growing tulip petal shaped domain, whereby we introduce a new method to describe the tulip petal growth explicitly. This work contributes to the theory of pattern formation of reaction-diffusion systems on growing domains applied to the fields of virology and botany.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.232
Teacher spread0.197 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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