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Record W4399762604 · doi:10.1139/cjc-2024-0023

Simple thiazole-based ligands for palladium(II) Suzuki–Miyaura aryl cross-coupling catalysts

2024· article· en· W4399762604 on OpenAlexafffundvenue
Clifford Agyei, Craig M. Robertson, Michael G. Campbell, Craig D. MacKinnon

Bibliographic record

VenueCanadian Journal of Chemistry · 2024
Typearticle
Languageen
FieldChemistry
TopicCatalytic Cross-Coupling Reactions
Canadian institutionsThunder Bay Regional Research InstituteLakehead University
FundersNatural Sciences and Engineering Research Council of CanadaLakehead University
KeywordsChemistryPalladiumArylCatalysisThiazoleCombinatorial chemistrySimple (philosophy)Coupling reactionOrganic chemistryAlkyl

Abstract

fetched live from OpenAlex

Two new palladium(II) catalysts, each containing a phenylthiazole ligand (2-methyl- (1a) and 2-amino-4-phenyl-1,3-thiazole (1b)), are prepared and characterized. The crystal structure of one, 2-methyl-4-phenyl)palladium(II) acetate (3a), is presented; it crystallizes as a dimer, with the ligand attached through the nitrogen on the thiazole and the ortho-carbon on the phenyl ring. The organometallic compounds can be used as catalysts in Suzuki–Miyaura aryl cross-coupling reactions. They are compatible with a wide range of functional groups, including carbonyls, amines, and phenols.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.277
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes3
Has abstractyes

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