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Record W4400061366 · doi:10.1137/23m1605582

Extinctions Caused by Host-Range Expansion

2024· article· en· W4400061366 on OpenAlexafffund
Pei Yu, Pantea Pooladvand, Mark M. Tanaka, Lindi M. Wahl

Bibliographic record

VenueSIAM Journal on Applied Dynamical Systems · 2024
Typearticle
Languageen
FieldMedicine
TopicZoonotic diseases and public health
Canadian institutionsWestern University
FundersAustralian Research CouncilNatural Sciences and Engineering Research Council of Canada
KeywordsHost (biology)Range (aeronautics)Computer scienceBiologyEcology

Abstract

fetched live from OpenAlex

Abstract. Nearly all emerging diseases in humans are a result of host-range expansion, in which a pathogen of one species evolves the ability to infect a new host species. To present a rigorous analysis of pathogen host-range expansion, we derive a Lotka–Volterra dynamical system with two competing host species and a single parasite species; the parasite infects only one of the host species. We provide a stability and bifurcation analysis of this model. We then ask what happens if the parasite evolves the ability to infect the alternate host, extending the model to include a parasite population with an expanded host range. We derive explicit global stability and bifurcation conditions for this four-dimensional model in terms of the system parameters. We demonstrate that only four outcomes may occur following the range expansion of a parasite or pathogen, and provide both local and global asymptotic stability conditions for these outcomes. While three of these outcomes were expected, the fourth is counterintuitive, predicting that host-range expansion can drive the original host species to extinction. For example, a native species could be driven to extinction by a longstanding native parasite if that parasite acquires the ability to infect a cultivated species. We briefly discuss the phenomena driving this unexpected prediction and its implications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.283
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes2
Has abstractno

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