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Record W4400203452 · doi:10.3899/jrheum.2023-1237

Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Living Treatment Recommendations for the Management of Axial Spondyloarthritis

2024· article· en· W4400203452 on OpenAlexaffvenueabout
Sherry Rohekar, Jordi Pardo Pardo, Reza Mirza, Sibel Zehra Aydın, Louis Bessette, Nicolas Richard, Dianne Mosher, Tristan Boyd, Jon Chan, Lihi Eder, Laura Passalent, Elie Karam, Bindu Nair, Glen Hazlewood, Shirley M. L. Tse, Dax G. Rumsey, Michel Zummer, Nigil Haroon, Robert D. Inman, Dafna D. Gladman

Bibliographic record

VenueThe Journal of Rheumatology · 2024
Typearticle
Languageen
FieldMedicine
TopicSpondyloarthritis Studies and Treatments
Canadian institutionsToronto Western HospitalUniversity of AlbertaSickKids FoundationUniversity of SaskatchewanWomen's College HospitalUniversité LavalHôpital Maisonneuve-RosemontWestern UniversityMcMaster Divinity CollegeCanadian Mental Health AssociationResearch CanadaUniversity Health NetworkOttawa HospitalArthritis Research Centre of CanadaUniversity of CalgaryCanadian Association of Emergency PhysiciansUniversity of Ottawa
FundersCelltrionCelltrion HealthcareAmgenPfizerEli Lilly and CompanyBristol-Myers Squibb
KeywordsAxial spondyloarthritisRheumatologyMedicineInternal medicineAssociation (psychology)Family medicineAnkylosing spondylitisPhysical therapySacroiliitisPsychology

Abstract

fetched live from OpenAlex

OBJECTIVE: To provide a set of living treatment recommendations that will give contemporary guidance on the management of patients with axial spondyloarthritis (axSpA) in Canada. METHODS: The Spondyloarthritis Research Consortium of Canada (SPARCC), in conjunction with the Canadian Rheumatology Association, organized a treatment recommendations panel composed of rheumatologists, researchers, allied health professionals, and a patient advocate. A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-ADOLOPMENT approach was used, in which existing guidelines were adopted or adapted to a Canadian context. Recommendations were also placed in a health equity framework. RESULTS: Fifty-six recommendations were made for patients with active axSpA, stable axSpA, active or stable axSpA, for comorbidities, and for assessment, screening, and imaging. Recommendations were also made for principles of management, disease monitoring, and ethical considerations. CONCLUSION: These living treatment recommendations will provide up-to-date guidance for the management of axSpA for Canadian practice. As part of the living model, they will be updated regularly as changes occur in the treatment landscape.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.033
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.952
Threshold uncertainty score0.349

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.033
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.004
Science and technology studies0.0050.002
Scholarly communication0.0030.001
Open science0.0030.002
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0110.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.318
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2024
Admission routes3
Has abstractyes

Explore more

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