A Twin Pregnancy With Undiagnosed Hereditary Hemorrhagic Telangiectasia With Severe Hypoxia
Bibliographic record
Abstract
During pregnancies with hereditary hemorrhagic telangiectasia (HHT), rare severe complications could be fatal. This study presents a Chinese immigrant with twin gestation with asymptomatic hypoxia. The pregnancy was complicated with fetal growth discordance, placental insufficiency, and preterm labor, which she delivered at 34 weeks via a primary cesarean section. The series of images showed multifocal bilateral pulmonary arteriovenous malformations and evidence of pulmonary hypertension. Postoperatively, the patient required high-flow oxygen and nitrogen oxide supply due to severe hypoxia. HHT was diagnosed with positive genetic testing of the ENG variant. She received pulmonary artery embolization and the hypoxia improved. The further workup of brain and liver arteriovenous malformations was negative. This study reviewed literature about HHT and its effects on pregnancies. The disease onset, the diagnostic process, and the management experience might provide clinical value for care providers and for future reference. J Clin Gynecol Obstet. 2024;13(2):48-50 doi: https://doi.org/10.14740/jcgo966
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".