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Record W4400295674 · doi:10.1093/humrep/deae108.263

O-224 “There might be two hundreds of us” - a qualitative study on the experience of meeting large numbers of same donor offspring

2024· article· en· W4400295674 on OpenAlexaffabout
Sabrina Zeghiche, Isabel Côté, Marcie LePine

Bibliographic record

VenueHuman Reproduction · 2024
Typearticle
Languageen
FieldMedicine
TopicOrgan Donation and Transplantation
Canadian institutionsUniversité du Québec en Outaouais
Fundersnot available
KeywordsOffspringMedicineBiologyComputational biologyGeneticsPregnancy

Abstract

fetched live from OpenAlex

Abstract Study question What are the experiences of donor-conceived people who discover large numbers (over 20) of same donor offspring, from a personal and relational point of view? Summary answer Participants reported feeling shocked by the number of donor-siblings. It led them to redefine their identity and their relations with their donor-siblings and the donor. What is known already The experience of discovering and meeting donor-siblings has been recently well documented. Yet, very little is known about how the size of the donor sibling group impacts this experience. A few studies have addressed the need to limit the number of offspring per donor. There is no consensus on what this limit should be and the regulations in that regard vary across countries. Although fears of incestuous relationships are still prevalent, policy discussions tend to focus mainly on the negative psychosocial impacts of discovering a large donor sibling group, however, no empirical evidence has allowed to support this concern. Study design, size, duration We conducted an exploratory study using a qualitative research design. Data collection was conducted in the Fall 2021 and Winter 2022 using a purposive sampling method. No geographical limitations were set for the data collection. Participants/materials, setting, methods The inclusion criteria for the recruitment of participants were: 1) donor-conceived adults aged 18 or over; 2) French or English-speaking; 3) with 20 or more donor-siblings. Data collection was carried out through online in-depth interviews. In total, 22 people took part in the study (16 women, 7 men and 1 non-binary person). They were aged between 21 and 76. Eight came from the US, 7 from the UK, 5 from Canada, and 2 from Germany. Main results and the role of chance The discovery of a large donor-sibling group provoked feelings of shock and surprise, combined with curiosity. Indeed, many participants mentioned that they had been disconcerted by this discovery, which often coincided with the disclosure of their mode of conception. Although the connections formed with their donor-siblings were generally described as enriching, their number was seen as an infringement of their singularity and individuality. The idea of having been “mass conceived” generated a certain unease, sometimes even a feeling of repulsion. Furthermore, the size of the group was often perceived either as a hindrance to the formation of meaningful bonds with donor-siblings, or as a burden. While some regretted not being able to know all their donor-siblings and mourned those impossible ties, others felt overwhelmed by the sheer number of exchanges, obligations, and unpredictable events their number entailed. Finally, a large donor-sibling group was seen by some as a potential obstacle to their relationship with the donor. For some, the fact that the donor donated his sperm on such a large scale questioned his integrity and motivations and depicted him in an unfavourable light. For others, being so numerous competing for his attention minimised their chances of establishing contact with him. Limitations, reasons for caution Despite the innovative nature of the study, the size of the sample and the variability of the experiences do not allow for definitive conclusions to be drawn and limit the understanding that can be gained from it. Further research should examine for example the context of online sperm donation. Wider implications of the findings With the democratization of direct-to-consumer DNA testing, more and more contacts between donor-siblings will occur. It is therefore important to examine how this phenomenon unfolds more specifically in the context of large donor-sibling groups. This will inform policy discussions on the need to limit the number of offspring per donor. Trial registration number Not applicable

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.419
Threshold uncertainty score0.264

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.390
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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