MétaCan
Menu
Back to cohort
Record W4400317002 · doi:10.1038/s41597-024-03585-6

Author Correction: PLAS-20k: Extended Dataset of Protein-Ligand Affinities from MD Simulations for Machine Learning Applications

2024· erratum· en· W4400317002 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueScientific Data · 2024
Typeerratum
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMachine Learning in Bioinformatics
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsAffinitiesBinding affinitiesLigand (biochemistry)Computer scienceComputational biologyArtificial intelligenceChemistryBiologyStereochemistryBiochemistryReceptor

Abstract

fetched live from OpenAlex

There was also an error in the Technical Validation section. In the original version we stated that a subset of 6842 complexes from PLAS-20k had experimental binding affinities whereas in fact this number was 6622. This error was made due to the original size of PLAS-20k being reduced from 20,000 to 19,500 complexes during the dataset creation but this reduction in size was not also accounted for in the validation sample. The correct (lower) sample size has been included in the manuscript (6842 replaced with 6622, where mentioned in the Technical Validation section and Figure 2 caption). Furthermore, the Pearson correlation coefficient (Rp) derived from this sample have been corrected to account for the correct sample size (originally stated as 0.50, now corrected to 0.53).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.225
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0020.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.324
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it