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Record W4400697361 · doi:10.47836/pjst.32.4.10

Borderline-DEMNET: A Workflow for Detecting Alzheimer’s and Dementia Stage by Solving Class Imbalance Problem

2024· article· en· W4400697361 on OpenAlexfundno aff
Neetha Papanna Umalakshmi, Simran Sathyanarayana, Thriveni Javarappa, Venugopal K.R.

Bibliographic record

VenuePertanika journal of science & technology · 2024
Typearticle
Languageen
FieldComputer Science
TopicImbalanced Data Classification Techniques
Canadian institutionsnot available
FundersCanadian Institutes of Health ResearchNational Institutes of HealthGenentechIXICOH. Lundbeck A/SServierEisaiNorthern California Institute for Research and EducationPfizerNovartis Pharmaceuticals CorporationF. Hoffmann-La RocheBiogenEli Lilly and CompanyBristol-Myers SquibbBioClinicaAlzheimer's Disease Neuroimaging InitiativeMeso Scale DiagnosticsAlzheimer's AssociationFoundation for the National Institutes of Health
KeywordsDementiaClass (philosophy)WorkflowStage (stratigraphy)MedicineComputer sciencePsychologyArtificial intelligenceDiseaseInternal medicineBiologyDatabase

Abstract

fetched live from OpenAlex

Alzheimer’s Disease (AD) is the leading cause of dementia, a broad term encompassing memory loss and other cognitive impairments. Although there is no known cure for dementia, managing specific symptoms associated with it can be effective. Mild dementia stages, including AD, can be treated, and computer-based techniques have been developed to aid in early diagnosis. This paper presents a new workflow called Borderline-DEMNET, designed to classify various stages of Alzheimer’s/dementia with more than three classes. Borderline-SMOTE is employed to address the issue of imbalanced datasets. A comparison is made between the proposed Borderline-DEMNET workflow and the existing DEMNET model, which focuses on classifying different dementia and AD stages. The evaluation metrics specified in the paper are used to assess the results. The framework is trained, tested, and validated using the Kaggle dataset, while the robustness of the work is checked using the ADNI dataset. The proposed workflow achieves an accuracy of 99.17% for the Kaggle dataset and 99.14% for the ADNI dataset. In conclusion, the proposed workflow outperforms previously identified models, particularly in terms of accuracy. It also proves that selecting a proper class balancing technique will increase accuracy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.012
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.001
Science and technology studies0.0010.000
Scholarly communication0.0010.002
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.291
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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