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Record W4400722153 · doi:10.1139/cjc-2024-0125

Platinum complexes with pyridyl derivatives of 1,2,4-triazole

2024· article· en· W4400722153 on OpenAlex
Anwar Abo-Amer, Paul D. Boyle, Richard J. Puddephatt

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
venuePublished in a venue whose home country is Canada.

Bibliographic record

VenueCanadian Journal of Chemistry · 2024
Typearticle
Languageen
FieldChemistry
TopicSynthesis and Characterization of Heterocyclic Compounds
Canadian institutionsWestern University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsChemistryTriazolePlatinumCombinatorial chemistry1,2,4-Triazole1,2,3-TriazoleMedicinal chemistryStereochemistryComputational chemistryOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

The chemistry of platinum(II) and platinum(IV) with the ligands 3,4,5-tris(2-pyridyl)-4-H-1,2,4-triazole, L1, and 3,5-di(2-pyridyl)-4-(4-pyridyl)-4-H-1,2,4-triazole, L2, is described. The ligand L1 forms platinum(II) complexes [PtXY(κ 2 -N, N′-L1)] (X, Y = Cl, Cl; Cl, Me; Me, Me) by chelation while ligand L2 forms either analogous chelate complexes [PtXY(κ 2 - N, N′-L2)] (X, Y = Cl, Me; Me, Me) or acts as a monodentate ligand in forming trans-[PtCl 2 (SMe 2 )(κ 1 -N-L2)], in which only the 4-pyridyl group is coordinated. The electron-rich dimethylplatinum(II) complexes undergo oxidative addition reactions with methyl iodide to give [PtIMe 3 (κ 2 -N, N′-L1)], or with dichloromethane to give [PtClMe 2 (CH 2 Cl)(κ 2 -N, N′-L1)] or [PtClMe 2 (CH 2 Cl)(κ 2 -N, N′-L2)], each of which is formed as a mixture of three isomers. Structure determinations of several of these complexes are reported.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.047
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.212
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it