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Record W4400778529 · doi:10.1242/jcs.263411

First person – Ke Shan and Trieu Le

2024· article· en· W4400778529 on OpenAlexaboutno aff

Bibliographic record

VenueJournal of Cell Science · 2024
Typearticle
Languageen
FieldMedicine
TopicErythrocyte Function and Pathophysiology
Canadian institutionsnot available
Fundersnot available
KeywordsBiologyEvolutionary biology

Abstract

fetched live from OpenAlex

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Ke Shan and Trieu Le are co-first authors on ‘ TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling’, published in JCS. Ke is a PhD candidate in the lab of Huanghe Yang at Duke University, School of Medicine, Durham, USA, investigating how TMEM16F scramblase-mediated collapse of phospholipid asymmetry controls biological functions, including blood coagulation, vessel formation and mechanical responses. Trieu performed this work while in the same laboratory and is now a postdoctoral fellow in the lab of Dr Sergio Grinstein and Dr Spencer for the Program in Cell Biology, Hospital for Sick Children, Toronto, Canada, investigating how the spatial organization of lipids, proteins, and macromolecules on the surface of cells contributes to cancer cells' evasion from immune surveillance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.055
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.090
Threshold uncertainty score0.299

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.055
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0080.004
Scholarly communication0.0080.007
Open science0.0010.005
Research integrity0.0040.012
Insufficient payload (model declined to judge)0.0900.054

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.265
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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