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Record W4400797598 · doi:10.1002/cctc.202400407

Alkyne Hydroamination Inhibited by Vinylidene Deactivation

2024· article· en· W4400797598 on OpenAlexafffund
Anne Marie M. Beardall, Devon E. Chapple, Nicolas Henao Ruiz, Paul D. Boyle, Johanna M. Blacquiere

Bibliographic record

VenueChemCatChem · 2024
Typearticle
Languageen
FieldChemistry
TopicCatalytic Alkyne Reactions
Canadian institutionsWestern University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsHydroaminationAlkyneChemistryCombinatorial chemistryCatalysisOrganic chemistry

Abstract

fetched live from OpenAlex

Abstract The synthesis and isolation of [Ru(Cp)(P Cy 2 N Ph 2 )(=C=CHPh]PF 6 and [Ru(Cp*)(P Cy 2 N Cy 2 )(=C=CHPh)]PF 6 was successfully accomplished. Use of these ruthenium vinylidene complexes for stoichiometric reactions with a variety of amines was performed. Upon reaction with alkyl amines, deprotonation of the C β hydrogen resulted in formation of acetylide complex [Ru(Cp*)(P Cy 2 N Ph 2 )(−C≡CPh)], and the species was confirmed through independent synthesis. In contrast, reaction of the less basic aryl amine aniline with [Ru(Cp)(P Cy 2 N Cy 2 )(=C=CHPh)]PF 6 resulted in outer sphere addition to give a Fischer carbene product.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.077
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.228
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2024
Admission routes2
Has abstractyes

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