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Record W4400906013 · doi:10.15353/cjo.v86i2.5450

Intermittent Anisocoria as Presenting Sign of Relapsing-Remitting Multiple Sclerosis

2024· article· en· W4400906013 on OpenAlexvenueno aff
C. R. Williams, L.H. Stevens

Bibliographic record

VenueCanadian journal of optometry/CJO. Canadian journal of optometry · 2024
Typearticle
Languageen
FieldMedicine
TopicOphthalmology and Eye Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsAnisocoriaMedicineMultiple sclerosisDiplopiaSpinal cordTransverse myelitisPupilAnesthesiaOphthalmologyPsychology

Abstract

fetched live from OpenAlex

A 36-year-old male presented for an examination reporting intermittent anisocoria of one week duration. Over a period of one-month, ocular findings consisted of intermittent and variable anisocoria, diplopia, and torsional nystagmus. A diagnosis of relapsing-remitting multiple sclerosis (MS) was made using the McDonald criteria based on brainstem syndrome, optic neuropathy, transverse myelitis symptoms, multifocal areas of demyelination in the spinal cord on MRI, and the absence of MS mimickers in lab work. In this case report, eye care providers are alerted to the possibility of intermittent anisocoria as a presenting sign of relapsing-remitting multiple sclerosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0090.004
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.327
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueCanadian journal of optometry/CJO. Canadian journal of optometrySame topicOphthalmology and Eye DisordersFrench-language works237,207