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Record W4400976668 · doi:10.1021/acs.jchemed.4c00250

Video-Based Bioinformatics Tutorials Developed as an Open Educational Resource to Improve Students’ Understanding and Practice in Data Science Analyses

2024· article· en· W4400976668 on OpenAlex
Zareen Amtul, Kelvin Vuu, Mark Lubrick, Arham A. Aziz, Mohammed A. S. Khan

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueJournal of Chemical Education · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsWilfrid Laurier UniversityUniversity of Windsor
FundersUniversity of California, San FranciscoNational Institutes of HealthUniversity of Windsor
KeywordsResource (disambiguation)Computer scienceScience educationData scienceOpen scienceEducational resourcesMedical educationMathematics educationMultimediaPsychologyMedicinePedagogy

Abstract

fetched live from OpenAlex

High Resolution Image Download MS PowerPoint Slide With the development of digital pedagogical resources, courses, and the recent COVID-19 pandemic, there has been a rise in the use of video-based learning (VBL) and teaching as one of the primary methods of instruction. Additionally, in recent years, bioinformatics has surfaced as an integral discipline in life sciences, where scientists are able to manipulate and analyze large sets of data. As a result, the need for digitally enhanced undergraduate and graduate teaching of basic bioinformatics skill sets of an applied nature has become increasingly high. Here, we designed and implemented a set of video-based bioinformatics tutorials as an open educational resource to be taught in an online synchronous, asynchronous, as well as HyFlex setting. These tutorials were designed to identify a ligand against unknown amino acid and nucleotide sequences to unveil their context in diverse species. This was achieved by navigating online bioinformatic databases, performing multiple sequence alignment, phylogenetic analyses, protein structure prediction/comparison, and docking. In the end, students also completed a survey questionnaire outlining their experience with the VBL. By the end of the term, VBL enabled the students to learn and apply bioinformatic concepts and tools to predict the protein structure from an unknown sequence and dock it with the ligands. Students rated VBL as one of the most powerful learning mediums out of many used as part of the module. Bioinformatic videos, besides capturing and distributing the bioinformatic information, also provided an invigorating environment where students better learned, understood, and retained the content.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.305
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.125
GPT teacher head0.492
Teacher spread0.367 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it