Evaluation of ChatGPT as a diagnostic tool for medical learners and clinicians
Bibliographic record
Abstract
BACKGROUND: ChatGPT is a large language model (LLM) trained on over 400 billion words from books, articles, and websites. Its extensive training draws from a large database of information, making it valuable as a diagnostic aid. Moreover, its capacity to comprehend and generate human language allows medical trainees to interact with it, enhancing its appeal as an educational resource. This study aims to investigate ChatGPT's diagnostic accuracy and utility in medical education. METHODS: 150 Medscape case challenges (September 2021 to January 2023) were inputted into ChatGPT. The primary outcome was the number (%) of cases for which the answer given was correct. Secondary outcomes included diagnostic accuracy, cognitive load, and quality of medical information. A qualitative content analysis was also conducted to assess its responses. RESULTS: ChatGPT answered 49% (74/150) cases correctly. It had an overall accuracy of 74%, a precision of 48.67%, sensitivity of 48.67%, specificity of 82.89%, and an AUC of 0.66. Most answers were considered low cognitive load 51% (77/150) and most answers were complete and relevant 52% (78/150). DISCUSSION: ChatGPT in its current form is not accurate as a diagnostic tool. ChatGPT does not necessarily give factual correctness, despite the vast amount of information it was trained on. Based on our qualitative analysis, ChatGPT struggles with the interpretation of laboratory values, imaging results, and may overlook key information relevant to the diagnosis. However, it still offers utility as an educational tool. ChatGPT was generally correct in ruling out a specific differential diagnosis and providing reasonable next diagnostic steps. Additionally, answers were easy to understand, showcasing a potential benefit in simplifying complex concepts for medical learners. Our results should guide future research into harnessing ChatGPT's potential educational benefits, such as simplifying medical concepts and offering guidance on differential diagnoses and next steps.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.055 | 0.255 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.004 | 0.003 |
| Open science | 0.002 | 0.007 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".