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Record W4401366406 · doi:10.1016/j.circv.2024.07.002

Valve-sparing root replacement. Toronto General Hospital experience

2024· article· en· W4401366406 on OpenAlexaffabout
María Ascaso, Christopher M. Feindel, Maral Ouzounian, Tirone E. David

Bibliographic record

VenueCirugía Cardiovascular · 2024
Typearticle
Languageen
FieldMedicine
TopicAortic Disease and Treatment Approaches
Canadian institutionsToronto General HospitalUniversity of Toronto
Fundersnot available
KeywordsMedicineRegurgitation (circulation)PerioperativeBicuspid aortic valveBicuspid valveSurgeryAortic valveAortic rootCardiologyAortic valve replacementInternal medicineAortaStenosis

Abstract

fetched live from OpenAlex

Aortic valve-sparing operations were developed at Toronto General Hospital in early 90's in an aim to preserve normal native aortic valve in the setting of root disease. This procedure has been mastered over the last 30 years. In this manuscript, we present our clinical and long-term outcomes using the implantation technique for both tricuspid and bicuspid valves, along with a detailed step-by-step explanation of the surgical technique, based on our experience. The reimplantation technique can be performed in many elective and urgent situations, but not all valves are suitable for optimal repair and an extensive valve morphology assessment using echocardiogram or intraoperative direct assessment, has been the key to achieve excellent long-term results. Our group showed 1% postoperative death with low pacemaker implantation (1.9%) and stroke rates (0.6%). All patients left the operating room with mild or less aortic regurgitation. Excellent perioperative results are achieved with a perfect and careful surgical technique. A detailed step-by-step description of the reimplantation technique is provided in this manuscript. Important technical considerations are included. Our series showed 84% 15-year survival and less than 10% recurrence of more than mild aortic regurgitation. The valve-sparing root replacement procedure provides excellent long-term clinical outcomes in terms of survival, freedom from reoperation and valve-related complications, along with stable aortic valve function, for both tricuspid and bicuspid aortic valve with favorable cusp morphology. La operación de preservación de la válvula aórtica fue desarrollada en el Hospital General de Toronto a inicios de los años noventa con el objetivo de preservar las válvulas aórticas nativas normales en el contexto de la enfermedad de la raíz. Este procedimiento se ha ido perfeccionado en los últimos 30 años. En este manuscrito presentamos nuestros resultados clínicos perioperatorios y a largo plazo utilizando la técnica de implantación aórtica tanto para válvulas tricúspides como bicúspides, junto con una explicación detallada paso a paso de la técnica quirúrgica, basada en nuestra experiencia. La técnica de reimplantación aórtica puede emplearse en situaciones electivas y urgentes, pero no todas las válvulas son aptas para una reparación óptima, haciendo necesaria una evaluación exhaustiva de la morfología valvular mediante ecocardiograma y mediciones directas intraoperatorias, siendo la clave para lograr excelentes resultados a largo plazo. Nuestro grupo presentó el 1% de muerte postoperatoria, con una baja tasa de implantación de marcapasos (1,9%) y de accidentes cerebrovasculares (0,6%). Todos los pacientes abandonaron el quirófano con regurgitación aórtica ligera o menor. Para unos resultados postoperatorios excelentes es necesario completar una técnica quirúrgica pulida y cuidadosa. En este manuscrito se ofrece una descripción detallada paso a paso de la técnica de reimplantación, incluyendo consideraciones técnicas importantes. Nuestra serie mostró una supervivencia a los 15 años del 84% y menos del 10% de recidiva de insuficiencia aórtica mayor a ligera. La operación de preservación de la válvula aórtica proporciona excelentes resultados clínicos a largo plazo en términos de supervivencia, tasa de reintervención y complicaciones relacionadas con la válvula, junto con una función estable de la válvula aórtica, tanto para válvulas aórticas tricúspides como para las bicúspides, con morfología de cúspide favorable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.061
Threshold uncertainty score0.121

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.264
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes2
Has abstractyes

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