Adolescent Idiopathic Scoliosis in Siblings Treated by Surgical Deformity Correction
Bibliographic record
Abstract
Adolescent idiopathic scoliosis (AIS) in siblings reflects genetic hypothesis; however, few studies have been published. Furthermore, to the best of our knowledge, there have been no reports in the literature of both siblings with AIS who underwent deformity corrections. A 15-year-old adolescent girl visited our clinic with back pain after recognition of the incidental findings of a scoliotic curve in the spine. Whole spine radiographs detected Lenke classification type 3CN. The patient underwent deformity correction with posterior instrumented fusion from T4 to L3 with thoracoplasty of the right 7th to 10th rib. Four years later, her 16-year-old younger brother also visited our clinic with back pain after recognition of the incidental findings of a scoliotic curve in the spine. Whole spine radiographs detected Lenke classification type 2AN. The patient underwent deformity correction with posterior instrumented fusion from T5 to L2 with thoracoplasty of the right 8th to 10th rib. In conclusion, we report on two siblings with AIS who underwent surgical treatment for different types of curves. They showed favorable outcomes after performing deformity correction with posterior instrumented fusion. Our rare case supports the underlying basis of genetic heterogeneity as a complex polygenic model.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".