MétaCan
Menu
Back to cohort
Record W4401388296 · doi:10.1211/pj.2024.1.325201

Closing the ethnicity gap in pharmacogenomics

2024· article· en· W4401388296 on OpenAlexaboutno aff

Bibliographic record

VenuePharmaceutical journal/˜The œpharmaceutical journal · 2024
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacogenetics and Drug Metabolism
Canadian institutionsnot available
Fundersnot available
KeywordsClosing (real estate)PharmacogenomicsEthnic groupMedicinePolitical scienceSociologyPharmacologyAnthropologyLaw

Abstract

fetched live from OpenAlex

Anil Kapoor came from a family of doctors. Having become a leading urologist and renal transplant surgeon at St Joseph’s, Hamilton, Canada, it came as a shock when — aged only 58 years — he received a diagnosis of colorectal cancer. He was prescribed a chemotherapy regimen called ‘FOLFOX’, which includes 5-fluorouracil (5-FU), a medicine […]

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.036
metaresearch head score (Gemma)0.085
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.036
Threshold uncertainty score0.189

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0360.085
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.006
Science and technology studies0.0010.004
Scholarly communication0.0050.007
Open science0.0010.006
Research integrity0.0030.007
Insufficient payload (model declined to judge)0.0090.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.245
GPT teacher head0.507
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

Explore more

Same venuePharmaceutical journal/˜The œpharmaceutical journalSame topicPharmacogenetics and Drug MetabolismFrench-language works237,207