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Record W4401702995 · doi:10.46439/hematol.3.015

The tip of the reproductive screening iceberg: ‘Every mother and every fetus matters’

2024· article· en· W4401702995 on OpenAlexaff
R. Douglas Wilson

Bibliographic record

VenueJournal of Clinical and Experimental Hematology · 2024
Typearticle
Languageen
FieldMedicine
TopicPrenatal Screening and Diagnostics
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMedicineFetusPregnancyObstetricsService (business)Genetic counselingIntensive care medicinePrenatal diagnosisPediatrics

Abstract

fetched live from OpenAlex

Introduction: This commentary expands on the routine pregnancy screening recommended during pregnancy, with genomic diagnosis and treatment following a positive fetal screening test indicating possible morbidity. Materials and Methods: Evidenced-based review article. Results/Discussion: An evidenced-based tool is identified for preconception risk assessment for maternal education; clinical service prioritization is promoted allowing for the ethnic and effective care for reproductive and pediatric care services; tertiary fetal diagnostic and treatment options are summarized; fetal therapy, as a quaternary service, is reviewed; human resource training is discussed. Fiscal considerations and barriers for fetal genomic and congenital malformation treatment are discussed. Conclusion: Prioritized healthcare service, preconception risk estimate counselling, genomic diagnosis, and fetal therapy for congenital malformations can reduce the neonatal and childhood morbidity but there may be fiscal and access to care barriers for many families.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.009
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.022
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.007
Scholarly communication0.0030.005
Open science0.0020.002
Research integrity0.0090.014
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.382
Teacher spread0.340 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Clinical and Experimental Hematology→Same topicPrenatal Screening and Diagnostics→French-language works237,207→