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Explainable machine learning for assessing upper respiratory tract of racehorses from endoscopy videos

2024· article· en· W4401730020 on OpenAlexafffund
Anas Tahir, Li Guo, Rabab Ward, Xinhui Yu, Andrew Rideout, Michael Hore, Zihan Wang

Bibliographic record

VenueComputers in Biology and Medicine · 2024
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicEffects of Environmental Stressors on Livestock
Canadian institutionsPlentyoffish Media (Canada)University of British ColumbiaUniversity of British Columbia Hospital
FundersMitacs
KeywordsEndoscopyRespiratory tractComputer scienceUpper endoscopyMedicineArtificial intelligenceRespiratory systemSurgeryAnatomy

Abstract

fetched live from OpenAlex

Laryngeal hemiplegia (LH) is a major upper respiratory tract (URT) complication in racehorses. Endoscopy imaging of horse throat is a gold standard for URT assessment. However, current manual assessment faces several challenges, stemming from the poor quality of endoscopy videos and subjectivity of manual grading. To overcome such limitations, we propose an explainable machine learning (ML)-based solution for efficient URT assessment. Specifically, a cascaded YOLOv8 architecture is utilized to segment the key semantic regions and landmarks per frame. Several spatiotemporal features are then extracted from key landmarks points and fed to a decision tree (DT) model to classify LH as Grade 1,2,3 or 4 denoting absence of LH, mild, moderate, and severe LH, respectively. The proposed method, validated through 5-fold cross-validation on 107 videos, showed promising performance in classifying different LH grades with 100%, 91.18%, 94.74% and 100% sensitivity values for Grade 1 to 4, respectively. Further validation on an external dataset of 72 cases confirmed its generalization capability with 90%, 80.95%, 100%, and 100% sensitivity values for Grade 1 to 4, respectively. We introduced several explainability related assessment functions, including: (i) visualization of YOLOv8 output to detect landmark estimation errors which can affect the final classification, (ii) time-series visualization to assess video quality, and (iii) backtracking of the DT output to identify borderline cases. We incorporated domain knowledge (e.g., veterinarian diagnostic procedures) into the proposed ML framework. This provides an assistive tool with clinical-relevance and explainability that can ease and speed up the URT assessment by veterinarians.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.006
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.302
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes2
Has abstractyes

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