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Record W4401918821 · doi:10.1186/s12859-024-05776-9

HBeeID: a molecular tool that identifies honey bee subspecies from different geographic populations

2024· article· en· W4401918821 on OpenAlexaff
Ravikiran Donthu, José Marcelino, Rosanna Giordano, Yudong Tao, Everett P. Weber, Arián Avalos, Mark Band, Tatsiana Akraiko, Shu‐Ching Chen, Maria Presa Reyes, Haiping Hao, Yarira Ortiz‐Alvarado, Charles A. Cuff, Eddie Pérez Claudio, Felipe N. Soto‐Adames, Allan H. Smith‐Pardo, William G. Meikle, Jay D. Evans, Tuğrul Giray, Faten Ben Abdelkader, Mike Allsopp, Daniel Ball, Susana B. Morgado, Shalva Barjadze, Adriana Correa-Benítez, Amina Chakir, David Báez, Nabor H. M. Chavez, Anne Dalmon, Adrian Bugeja Douglas, Carmen Fraccica, Hermógenes Fernández‐Marín, Alberto Galindo‐Cardona, Ernesto Guzmán‐Novoa, Meral Kence, Joseph Kilonzo, Mert Kükrer, Yves Le Conte, Gaetana Mazzeo, Fernando Mota, Elliud Muli, Devrim Oskay, José A. Ruiz-Martínez, Eugenia Oliveri, Igor Pichkhaia, Abderrahmane Romane, Cesar Guillen Sanchez, Evans Sikombwa, Alberto Satta, Alejandra A. Scannapieco, Brandi Stanford, Victoria Soroker, Rodrigo A. Velarde, Monica Vercelli, Zhi Huang

Bibliographic record

VenueBMC Bioinformatics · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInsect and Arachnid Ecology and Behavior
Canadian institutionsUniversity of Guelph
FundersAnimal and Plant Health Inspection ServiceUniversity of Illinois at Urbana-ChampaignOrta Doğu Teknik ÜniversitesiOffice of International Science and EngineeringU.S. Department of AgricultureFlorida International UniversityUppsala UniversitetNational Science Foundation
KeywordsSubspeciesHoney beeBiologyPollinatorLinear discriminant analysisHierarchical clusteringEcologyCluster analysisArtificial intelligenceComputer sciencePollenPollination

Abstract

fetched live from OpenAlex

BACKGROUND: Honey bees are the principal commercial pollinators. Along with other arthropods, they are increasingly under threat from anthropogenic factors such as the incursion of invasive honey bee subspecies, pathogens and parasites. Better tools are needed to identify bee subspecies. Genomic data for economic and ecologically important organisms is increasing, but in its basic form its practical application to address ecological problems is limited. RESULTS: We introduce HBeeID a means to identify honey bees. The tool utilizes a knowledge-based network and diagnostic SNPs identified by discriminant analysis of principle components and hierarchical agglomerative clustering. Tests of HBeeID showed that it identifies African, Americas-Africanized, Asian, and European honey bees with a high degree of certainty even when samples lack the full 272 SNPs of HBeeID. Its prediction capacity decreases with highly admixed samples. CONCLUSION: HBeeID is a high-resolution genomic, SNP based tool, that can be used to identify honey bees and screen species that are invasive. Its flexible design allows for future improvements via sample data additions from other localities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.107
Threshold uncertainty score0.702

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.258
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2024
Admission routes1
Has abstractyes

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