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Record W4402126733 · doi:10.1016/j.burns.2024.08.024

BURN-OP: A screening tool for identifying a symptomatically distinct cluster of burn patients with the greatest healthcare needs at discharge

2024· article· en· W4402126733 on OpenAlexaff
Sarthak Sinha, Caleb Small, Eddie Guo, Myriam Verly, Rohit Arora, Aydin Herik, E Jonsson, A. Robertson Harrop, Jeff Biernaskie, Claire Temple‐Oberle, Vincent Gabriel

Bibliographic record

VenueBurns · 2024
Typearticle
Languageen
FieldMedicine
TopicBurn Injury Management and Outcomes
Canadian institutionsAlberta Children's HospitalHotchkiss Brain InstituteAlberta Bone and Joint Health InstituteUniversity of Calgary
FundersNational Institute on Disability, Independent Living, and Rehabilitation ResearchU.S. Department of Health and Human Services
KeywordsMedicineCluster (spacecraft)Health careBurn injuryMedical emergencyIntensive care medicineSurgery

Abstract

fetched live from OpenAlex

OBJECTIVE: To identify burn patients needing intensive rehabilitation based on discharge symptoms. METHODS: We conducted a retrospective analysis of 1049 adult burn patients recruited to the Burn Injury Model System National Database. Using unsupervised hierarchical clustering, we identified three distinct patient clusters based on discharge symptoms and compared their clinical and demographic profiles, long-term rehabilitative needs, and self-reported quality of life. We also developed a weighted BUrn Rehabilitative Needs - OutPatient (BURN-OP) to prospectively identify patients with highest rehabilitative needs. RESULTS: Three burn patient clusters were identified: Cluster 1 with low, Cluster 2 with moderate, and Cluster 3 with high symptom burdens. Cluster 3, comprising 6 % of discharged patients, had notably longer hospital stays, older age at burn, larger total body surface area (TBSA), increased days on ventilator, a higher number of surgical procedures, concomitant inhalation injury, and higher weight loss from admission to discharge. Cluster 3 patients preferentially utilized a wide spectrum of rehabilitative services (including physiotherapy, occupational therapy, speech-language pathology, social work, psychologic services, vocational services) extending up to 2 years post-discharge. Their self-reported health outcomes were worse, with greater limitations in work/activity and elevated pain interference persisting 5-years post-discharge. BURN-OP demonstrated high specificity (98.99 %) and accuracy (96.19 %, ROC AUC: 0.93) in identifying Cluster 3 patients at discharge. CONCLUSIONS: We identify distinct burn patient clusters based on discharge symptoms, with Cluster 3 exhibiting the highest post-discharge healthcare needs. BURN-OP (https://burn-op.streamlit.app/) identifies high-risk patients, offering a tool for prioritizing interventions and designing trials that mitigate risk of Cluster 3 membership.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.487

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.301
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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