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Record W4402236753 · doi:10.1007/978-3-031-56806-0_77

The Power of Genomics

2024· book-chapter· en· W4402236753 on OpenAlexaff
Kimiora Henare, Mackenzie K. Connon, Nadine R. Caron, Alex Brown

Bibliographic record

Venuenot available
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRace, Genetics, and Society
Canadian institutionsPositive Living North
Fundersnot available
KeywordsGenomicsComputational biologyBiologyComputer scienceGeneticsGenomeGene

Abstract

fetched live from OpenAlex

The promise of genomics-guided precision oncology is highlighted by recent approvals of molecularly guided therapies coupled with companion diagnostic tests. A critical limitation of genomics-guided oncology is that it is unlikely to serve Indigenous cancer patients unless Indigenous rights-based approaches to genomics-guided cancer research and clinical care are prioritized. Relevant Indigenous datasets that can support precision oncology are needed. Indigenous access to and governance over key infrastructure are needed. We must grow and empower an Indigenous workforce with subject matter expertise and clinical acumen to ensure that genomics-guided precision oncology can sustainably benefit Indigenous cancer patients

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.013
Threshold uncertainty score0.043

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0020.012
Scholarly communication0.0050.008
Open science0.0010.003
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0130.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.218
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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