MétaCan
Menu
Back to cohort
Record W4402316253 · doi:10.1038/s41565-024-01754-7

A translational framework to DELIVER nanomedicines to the clinic

2024· review· en· W4402316253 on OpenAlexaff
Paul Joyce, Christine Allen, Marı́a José Alonso, Marianne Ashford, Michelle S. Bradbury, Matthieu Germain, Maria Kavallaris, Róbert Langer, Twan Lammers, Maria Teresa Peracchia, Amirali Popat, Clive A. Prestidge, Cristianne J.F. Rijcken, Bruno Sarmento, Ruth Schmid, Avi Schroeder, Santhni Subramaniam, Chelsea R. Thorn, Kathryn A. Whitehead, Chun‐Xia Zhao, Hélder A. Santos

Bibliographic record

VenueNature Nanotechnology · 2024
Typereview
Languageen
FieldMaterials Science
TopicNanoparticle-Based Drug Delivery
Canadian institutionsUniversity of Toronto
FundersAgencia Estatal de InvestigaciónInstituto de Salud Carlos IIITour de CureMinisterio de Economía y CompetitividadBundesministerium für Bildung und ForschungDeutsche ForschungsgemeinschaftUniversitair Medisch Centrum GroningenCancer Council NSWNational Health and Medical Research CouncilAcademy of FinlandCancer Council South AustraliaMedical Research CouncilEuroNanoMed IIIGovernment of South AustraliaHospital Research Foundation
KeywordsNanotechnologyTranslational researchComputer scienceMedicineData scienceMaterials sciencePathology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.001
Scholarly communication0.0020.003
Open science0.0010.001
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.348
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations219
Published2024
Admission routes1
Has abstractno

Explore more

Same venueNature NanotechnologySame topicNanoparticle-Based Drug DeliveryFrench-language works237,207