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Record W4402320934 · doi:10.5376/tgg.2024.15.0008

<i>Triticeae</i> and Gluten: Genetic Bases of Wheat Allergies and Sensitivities <i>Triticeae</i>

2024· article· en· W4402320934 on OpenAlexvenueno aff
Jin Zhou, Xuemei Liu

Bibliographic record

VenueTriticeae Genomics and Genetics · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicTransgenic Plants and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsTriticeaeGlutenWheat glutenChemistryBiologyGeneticsBiochemistryGeneGenome

Abstract

fetched live from OpenAlex

The Triticeae  tribe, including major cereals such as wheat, oats, and rye, plays a crucial role in global agriculture and human nutrition. Gluten, the main protein complex in wheat, is indispensable in food processing due to its unique viscoelastic properties but is also a major concern for health issues such as celiac disease (CD), non-celiac wheat sensitivity (NCWS), and wheat allergies. This study aims to review the genetic bases of wheat allergies and sensitivities, including the structure and function of gluten proteins, the genetic variability of allergenic gluten proteins, and diagnostic methods. By exploring the mechanisms of NCWS and the genetic predisposition to CD, this study will also introduce the latest advances in genomic research and molecular breeding techniques, particularly the application of CRISPR/Cas9 gene editing technology in reducing wheat allergens. The goal is to integrate genomic approaches and advanced breeding techniques to develop hypoallergenic wheat varieties, thereby improving the safety and quality of wheat products to meet the growing consumer demand for allergen-free foods. This study hopes to provide new insights into the understanding of wheat allergies and sensitivities and offer scientific basis and practical guidance for developing safer and higher-quality wheat products in the future.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.810
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.227
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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