Embracing the Olympic spirit: pioneering cardiac care insights from the 2024 European Society of Cardiology scientific meeting and more!
Bibliographic record
Abstract
As the world revels in the afterglow of the spectacular 2024 Olympic Games in Paris, celebrating human endurance and triumph, we also mark the incredible breakthroughs presented at the 2024 European Society of Cardiology (ESC) congress in London. This issue of the European Heart Journal—Acute Cardiovascular Care features major advancements and insights in cardiac care, echoing the Olympic spirit of striving for excellence. In this issue, we put highlights from the London 2024 ESC scientific congress in perspective that are relevant to acute cardiac and intensive care. The STOP-or-NOT trial offers critical findings on the use of renin–angiotensin system inhibitors, providing data to guide decisions often faced in the intensive care unit. Meanwhile, the TIGHT-K trial investigates the role of potassium supplementation in preventing atrial fibrillation post-cardiac surgery, a common and challenging complication. The ABYSS trial examines the implications of β-blocker interruption in patients with a history of myocardial infarction, adding depth to our understanding of the optimal post-myocardial infarction pharmacotherapeutic regimen. Additionally, the SCOFF trial evaluates the impact of fasting vs. non-fasting before cardiac catheterization procedures, offering evidence that may reshape pre-procedural practices. But there is more… A groundbreaking study by Frea and colleagues explores comprehensive non-invasive haemodynamic assessment in acute heart failure-related cardiogenic shock (HF-CS). Conducted in 101 patients with Society for Cardiovascular Angiography and Interventions shock stage ≥ B, the study reveals a strong correlation between echocardiographic and invasive measurements for cardiac index, systolic pulmonary artery pressure, right atrial pressure, and cardiac power output, with Pearson r values exceeding 0.8. This research underscores the potential of non-invasive echocardiographic evaluations to offer reliable and readily available haemodynamic profiling in critical settings, potentially enhancing patient management and outcomes. Notably, the report introduces the first prospective validation of echocardiographic estimation of pulmonary artery pulsatility index, affirming its prognostic significance and advocating for broader use of echocardiography in assessing haemodynamics during HF-CS. In another pivotal study, Christina Byrne et al. delve into the relevance of age and hypertension for blood pressure targets in comatose survivors of cardiac arrest. Utilizing data from the BOX trial, which included 789 patients randomized to either a low mean arterial blood pressure (MAP) target (63 mmHg) or a high MAP target (77 mmHg), the study reports that older patients and those with a history of hypertension did not significantly benefit from a higher MAP target post-out-of-hospital cardiac arrest (OHCA). Interestingly, younger patients may derive more benefit from a lower MAP target strategy, suggesting that a restrictive vasopressor strategy with a lower MAP target might be sufficient for all individuals resuscitated from OHCA, irrespective of their hypertension status. In addition to the need for further randomized studies, these findings underscore the need for personalized blood pressure management strategies in post-resuscitation care, particularly considering patient age. Finally, the manuscript by Uwe Zyemer et al. (reference) explores whether patients with infarct-related cardiogenic shock, like those in the Dan-Ger-Shock trial,1 benefit from veno-arterial extracorporeal membrane oxygenation treatment. This individual patient data meta-analysis included 202 patients from four randomized clinical trials. Despite the study's limited sample size, it provides the most comprehensive data to date on this topic. As we delve into the September issue, let us embrace the spirit of the Olympics—celebrating human potential and the relentless pursuit of excellence. Discover the latest in acute cardiac and intensive care and join us in pioneering innovative solutions to the evolving challenges in cardiovascular medicine. Together, we can continue to push the boundaries of what is possible, improving patient outcomes and shaping the future of cardiac care. Enjoy! Pascal Vranckx, David Morrow, Sean van Diepen, Frederik Verbrugge editors.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.011 | 0.030 |
| Meta-epidemiology (narrow) | 0.003 | 0.001 |
| Meta-epidemiology (broad) | 0.003 | 0.002 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.007 | 0.006 |
| Open science | 0.003 | 0.002 |
| Research integrity | 0.013 | 0.023 |
| Insufficient payload (model declined to judge) | 0.009 | 0.006 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".