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Record W4402346765 · doi:10.1016/j.ajt.2024.03.024

An unexpected biliary complication in a patient with remote liver transplant

2024· article· en· W4402346765 on OpenAlexaff
Farah Ladak, Anand Ghanekar

Bibliographic record

VenueAmerican Journal of Transplantation · 2024
Typearticle
Languageen
FieldMedicine
TopicPediatric Hepatobiliary Diseases and Treatments
Canadian institutionsToronto General HospitalUniversity Health Network
Fundersnot available
KeywordsMedicineComplicationLiver transplantationGeneral surgerySurgeryTransplantation

Abstract

fetched live from OpenAlex

Statement of NeedStandard surgical practices used in contemporary liver transplantation have evolved considerably since the 1980s, when relatively poor results by today's standards motivated experimentation with a wide variety of surgical techniques.With ongoing refinements in medical management of transplant recipients, some patients who received liver transplants in that era continue to survive.Because these patients may require abdominal surgical care, today's surgeons must be familiar with historical practices in liver transplant surgery.Remote liver transplants represent a distinct subset of cases where biliary tract anatomy or reconstruction may deviate significantly from what the standard of care has been for more than 25 years, predating the training of most currently practicing liver transplant surgeons and, thereby, exposing a potential gap in knowledge.This case illustrates biliary complications unique to this population and underscores the need for transplant surgeons and trainees to possess an understanding of historical biliary reconstruction techniques, the nuances of remote liver transplants, and the specific considerations required in immunocompromised patients. Purpose of ActivityThe purpose of this activity is to enhance participant understanding of the evolution in biliary tract reconstruction in liver transplant recipients.It aims to promote an appreciation for the historical and contemporary approaches, as well as diagnostic considerations, pertaining to biliary anatomy that may not align with modern practice.In addition, the activity seeks to underscore the importance of accounting for the added complexity introduced by immunosuppression when conducting surgical procedures on transplant patients. Identification of Practice GapAddressing long-term transplant survivors from the 1980s-1990s, a period marked by procedures distinct from contemporary practices, emerges as an uncommon challenge.With seasoned surgeons from the pioneering era approaching retirement, there is a genuine risk of losing invaluable insights into historical techniques.It becomes crucial to impart this knowledge to the younger generation of practitioners, ensuring they are equipped with a comprehensive understanding of past practices that may unexpectedly become pertinent in today's surgical landscape. Learning Objectives-Describe the different technical approaches to biliary tract reconstruction in liver transplant.-Recognize the potential for unique biliary complications and presentations in patients with remote liver transplant.-Demonstrate appropriate management of acute surgical problems in immunocompromised patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0030.002
Science and technology studies0.0050.002
Scholarly communication0.0030.003
Open science0.0020.003
Research integrity0.0080.007
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.261
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractno

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