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Record W4402452749 · doi:10.1136/bmjgh-2024-015862

A call to bridge the diagnostic gap: diagnostic solutions for neonatal sepsis in low- and middle-income countries

2024· article· en· W4402452749 on OpenAlexaff
Birgitta Gleeson, Cecilia Ferreyra, Kara Palamountain, Shevin T. Jacob, Naomi Spotswood, Niranjan Kissoon, Yasir Bin Nisar, Felicity Fitzgerald, Sarah Murless-Collins, Uduak Okomo, James Cross, Elizabeth Molyneux, Erwan Piriou, Kenechukwu K. Iloh, Data Santorino, David A. Goldfarb, Alex Stevenson, Rebecca Kirby, Brooke E Nichols, Benjamin Blümel, Cassandra Kelly‐Cirino, Timothy R. Walsh, Lizel Georgi Lloyd, Sara Liaghati-Mobarhan

Bibliographic record

VenueBMJ Global Health · 2024
Typearticle
Languageen
FieldMedicine
TopicNeonatal and Maternal Infections
Canadian institutionsBC Children's Hospital
FundersDepartment of Health and Social CareBundesministerium für Bildung und ForschungNational Institute for Health and Care ResearchAcademy of Medical SciencesWorld Health Organization
KeywordsLow and middle income countriesBridge (graph theory)Neonatal sepsisDiagnostic testSepsisPublic healthMedicineIntensive care medicineEconomicsEnvironmental healthPublic economicsPediatricsDeveloping countryEconomic growthNursingSurgery

Abstract

fetched live from OpenAlex

The first month of life is the most critical period for an infant’s survival, yet the most neglected for the provision of quality care. Each year, an estimated 2.3 million neonates die in their first month of life. 1 Sepsis alone is responsible for 7.3% of all neonatal deaths worldwide, with a significant burden falling on low- and middle-income countries (LMICs).2 While there remains an ongoing debate regarding the definition of neonatal sepsis, it is broadly described as a suite of non-specific signs that may include fever or hypothermia, respiratory distress, cyanosis and apnoea, feeding difficulties, lethargy or irritability, hypotonia, seizures, bulging fontanelle, poor perfusion, bleeding problems, abdominal distention, hepatomegaly, unexplained jaundice or more importantly ‘just not looking right’.3

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.040
metaresearch head score (Gemma)0.111
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.049
Threshold uncertainty score0.210

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0400.111
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0030.002
Science and technology studies0.0050.008
Scholarly communication0.0140.025
Open science0.0050.018
Research integrity0.0280.037
Insufficient payload (model declined to judge)0.0490.015

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.374
Teacher spread0.338 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2024
Admission routes1
Has abstractyes

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